Background: Craniospinal irradiation (CSI) of medulloblastoma poses technological challenges due to the involvement of large treatment volume. Commonly, the whole treatment length is covered with two different isocentric plans in which the junction is shifted after every five fractions to overcome the possibility of hot and cold spot.Objective: This study aims to evaluate dosimetrically and cli...

The technical development described herein was undertaken to create a tumor ablation treatment system that consists of a software component and a robotic hardware component. First, the software treatment planning system enables applicator placement planning before tumor ablation. For example, it allows creation of overlapping ablations with the goal of treating larger tumors. Second, the roboti...

Electrochemotherapy uses electroporation for enhancing chemotherapy. Electrochemotherapy can be performed using standard operating procedures with predefined electrode geometries, or using patient-specific treatment planning to predict electroporation. The latter relies on realistic computer models to provide optimal results (i.e. electric field distribution as well as electrodes' position and ...

TRiP98 is a treatment planning program for radiotherapy with scanned ion beams. It was developed at GSI and has been successfully used in clinical routine from 1997-2008 for over 400 patients, predominantly with head and neck tumors [1,2]. The treatment of tumors within moving organs, such as lung tumors, with scanned ion beams involves additional complexity of the beam delivery and the treatme...