BACKGROUND The incidence of tuberculosis has increased among South African gold miners despite comprehensive control programmes, including a radiological screening programme. No data are available as to the optimal frequency of screening. The aim of this study was to compare 6-monthly and 12-monthly radiological screening for active tuberculosis case-finding. METHODS Employees of a gold minin...

BACKGROUND Tuberculosis is re-emerging as an important health problem in industrialised countries. Uncertainty surrounds the effect of public-health control options. We therefore aimed to assess a programme to promote screening for tuberculosis in a UK primary health care district. METHODS In a cluster randomised controlled trial, we randomised 50 of 52 (96%) eligible general practices in Hac...

Using a mouse model for genetic analysis of host resistance to virulent Mycobacterium tuberculosis, we have identified a genetic locus sst1 on mouse chromosome 1, which controls progression of pulmonary tuberculosis. In vitro, this locus had an effect on macrophage-mediated control of two intracellular bacterial pathogens, M. tuberculosis and Listeria monocytogenes. In this report, we investiga...

The link between diabetes mellitus and tuberculosis has been recognised for centuries. In recent decades, tuberculosis incidence has declined in high-income countries, but incidence remains high in countries that have high rates of infection with HIV, high prevalence of malnutrition and crowded living conditions, or poor tuberculosis control infrastructure. At the same time, diabetes mellitus p...

a nested polymerase chain reaction (pcr) assay with two pairs of primers was applied for the detection of m. tuberculosis complex dna in specimens of 51 patients. of these, 31 clinically diagnosed patients (group i) recruited from july 1996 to june 1997 were given antituherculous chemotherapy from one to six months with standard daily regimen (isaniazid, 5 mg/kg; rifampin, 10 mg/kg; pyrazinamit...

Indonesia is among the top three countries globally with highest tuberculosis burden. During past decades, Indonesian health authorities have struggled to improve care quality in facilities by optimizing regulation and strengthening private sector contributions. The coronavirus disease 2019 (COVID-19) pandemic has hardly affected system, including National Tuberculosis Control Program. While en...

Objective: Dysfunctional beliefs of tuberculosis patients have pivotal role in treatment and development of their serious psychiatric problems. Cognitive group psychotherapy has been utilized to manage the dysfunctional beliefs. Methods: In a quasi-experimental study and a pretest and posttest design, 24 male tubercular patients were selected by convenient sampling and then randomly assigned...