Magnetic resonance spectroscopic imaging (MRSI) is currently used clinically in conjunction with anatomical MRI to assess the presence and extent of brain tumors and to evaluate treatment response. Unfortunately, the clinical utility of MRSI is limited by significant variability of in vivo spectra. Spectral profiles show increased variability because of partial coverage of large voxel volumes, ...

Angiogenesis is a hallmark of tumor pathogenesis. Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis and its inhibition has become a successful approach to antitumor therapy across tumor types. The VEGF gene is highly polymorphic with multiple common single nucleotide polymorphisms (SNPs) in the promoter, 5' untranslated region and 3' untranslated region. There is...

Angiogenesis is a hallmark of tumor pathogenesis. Vascular endothelial growth factor (VEGF) is a critical regulator of angiogenesis and its inhibition has become a successful approach to antitumor therapy across tumor types. The VEGF gene is highly polymorphic with multiple common single nucleotide polymorphisms (SNPs) in the promoter, 5′ untranslated region and 3′ untranslated region. There is...

In recent years, the tumor microenvironment (TME) has been identified as an important factor influencing the growth and metastasis of the tumor. In the TME, different classes of inflammatory cells have been found to exert either a proor anti-tumor effect. This has resulted in a growing need to utilize immunohistochemistry to label these leukocyte populations, thereby allowing for the cells to b...

Segmentation of images holds an important position in the area of image processing. It becomes more important while typically dealing with medical images where presurgery and post surgery decisions are required for the purpose of initiating and speeding up the recovery process. Computer aided detection of abnormal growth of tissues is primarily motivated by the necessity of achieving maximum po...

abstract the temperature of water entering the soil or variation in soil temperature has a direct impact on soil hydraulic conductivity via the effect on water viscosity. in this research, the time variability of soil saturated hydraulic conductivity (ks) was studied. the relation between soil temperature and fluid viscosity with hydraulic conductivity were also studied. the necessary experimen...

background and objective: obstructive sleep apnea syndrome (osas) is a prevalent disease in adults. limited evidence regarding the effect of severity of sleep apnea and depression on heart rate variability (hrv) indices exists. hence, we decided to focus on the association between hrv and severity of osas based on depression score. materials and methods: a total of 193 patients with confirmed o...

objective: the theraputic exercise is regarded as one of the most important theraputic interventions in the chronic low back pain patients. stabilization exercise is among the most significant practical ones in these patients. the study of the effects of these exercises on the variability of trunk muscles postural strategies and the ability in normalizing these strategies are among the uncertai...

having knowledge about genetic relationships among accessions is necessary for developing breeding strategies to produce improved cultivars. in present study, genetic diversity and inter-relationship among 29 genotypes of citrus were comparatively analyzed using morphological and rapd markers. significant variability was observed among citrus genotypes for 61 quantitative and qualitative morpho...