objective pfeiffer syndrome is as rare as apert syndrome in the western population. this condition is very rare in the asian population. at the best of our knowledge this is the first genetically proven case report from iran. the authors report with a review of literature, the case of a infant with pfeiffer syndrome, manifested by lacunar skull, ventriculomegaly, bicoronal craniosynostosis,fron...

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background: resistin and ghrelin are hormones that have roles in the glucose and lipid homeostasis and weight regulation. human studies regarding resistin and ghrelin in diabetic patients are scarce, especially in the cases of normotensive and non-obese patients. this study was designed to illuminate some of the missing points.methods: eighty diabetic patients and eighty healthy individuals par...

health care system is organized to achieve more efficiency as well as developing public equity and providing access to the first, second and third levels of services. family physician is in the first line of the health care system; in other words, family physician is the health system’s goalkeeper. according to classification of health services, gaining access to specialized services becomes po...

celiac disease in type i diabetes millitus; a case report

objective: type 2 diabetes (t2d) as a complex disease is the result of genetically heterogeneous factors and environmental issues interaction. linkage and small-scale candidate gene studies were successful in identification of genetic susceptibilities of monogenic form of diseases. however, they were largely unsuccessful while applying to the more common forms of disease. by designing genome wi...

The diversity of contemporary swine influenza virus (SIV) strains impedes effective immunization of swine herds. Mucosally delivered, attenuated virus vaccines are one approach with potential to provide broad cross-protection. Reverse genetics-derived H3N2 SIV virus with truncated NS1 (NS1Δ126 TX98) is attenuated and immunogenic when delivered intranasally in young pigs. We analyzed T-cell prim...