نتایج جستجو برای: tyrosinemia type ii

تعداد نتایج: 1796109  

Journal: :Acta biochimica Polonica 2009
Sergey Molchanov Adam Gryff-Keller

Triketone herbicides are inhibitors of 4-hydroxyphenylpyruvate dioxygenase (HPPD), a key enzyme of the tyrosine transformation pathway, common for plants and animals. One of these herbicides, 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione (NTBC), is so selective and efficient that it can be applied as a medicine in a hereditary metabolic disease - tyrosinemia type I. In this paper ...

Azam Jafaryfard*, Elham Zahedi Mohammad Hasan Ghosian Mohsen Khalili,

Background and Objective: Several studies have found that diazepam decreases serum glucose. Meanwhile, glibenclamide is commonly used in diabetes treatment. The objective of this study was to survey the treatment impact of diazepam and glibenclamide on blood glucose and serum lipids in mice with type II diabetes. Materials and Methods: In this study, 32 male rats were divided into four groups,...

Journal: :تحقیقات نظام سلامت 0
آذر طل دکتری تخصصی، گروه آموزش بهداشت و ارتقای سلامت، دانشکده بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایران فرشته مجلسی استاد، گروه آموزش بهداشت و ارتقای سلامت، دانشکده بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایران عباس رحیمی فروشانی دانشیار، گروه آمار و اپیدمیولوژی، دانشکده بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایران داود شجاعی زاده استاد، گروه آموزش بهداشت و ارتقای سلامت، دانشکده بهداشت، دانشگاه علوم پزشکی تهران، تهران، ایران بهرام محبی استادیار، گروه قلب و عروق، دانشکده پزشکی، دانشگاه علوم پزشکی تهران، تهران ، ایران

background: psychological and behavioral domains are important in coping with type ii diabetes. this study was conducted to assess supportive and coping obstacles in living with type ii diabetes among patients who visited hospitals affiliated to tehran university of medical sciences (tums). methods: this was a cross-sectional study with 600 subjects who participated in the study. data collectio...

Journal: :PLoS Genetics 2006
Darius Balciunas Kirk J Wangensteen Andrew Wilber Jason Bell Aron Geurts Sridhar Sivasubbu Xin Wang Perry B Hackett David A Largaespada R. Scott McIvor Stephen C Ekker

Viruses and transposons are efficient tools for permanently delivering foreign DNA into vertebrate genomes but exhibit diminished activity when cargo exceeds 8 kilobases (kb). This size restriction limits their molecular genetic and biotechnological utility, such as numerous therapeutically relevant genes that exceed 8 kb in size. Furthermore, a greater payload capacity vector would accommodate...

Journal: :Applied and environmental microbiology 2015
Thi Thanh My Pham Mohammad Sondossi Michel Sylvestre

In this work, we examined the profile of metabolites produced from the doubly para-substituted biphenyl analogs 4,4'-dihydroxybiphenyl, 4-hydroxy-4'-chlorobiphenyl, 3-hydroxy-4,4'-dichlorobiphenyl, and 3,3'-dihydroxy-4,4'-chlorobiphenyl by biphenyl-induced Pandoraea pnomenusa B356 and by its biphenyl dioxygenase (BPDO). 4-Hydroxy-4'-chlorobiphenyl was hydroxylated principally through a 2,3-diox...

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