UNLABELLED This study was aimed to assess the antioxidant enzymatic and non-enzymatic compounds in semen of infertile men. Seventy-four infertile patients were grouped according to their clinical diagnosis: genitourinary infection, varicocele, idiopathic infertility. Semen samples of fertile men represent the control. Semen characteristics were evaluated by light and transmission electron micro...

The higher frequency of varicocele in men with infertility has drawn attention and resulted in increased research at the molecular level towards treatments. The aim of this study was to investigate the role of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its receptors in varicocele-induced testicular dysfunction in an experimental rat model. The rats were divided in...

Objective(s): Varicocele is an abnormal dilation in the testicular vein, which can cause hypoxia, reactive oxygen species accumulation, elevation in testicular temperature, and promote apoptosis and increase proinflammatory cytokine production. According to the varicocele pathophysiology, it is possible that a group of cytosolic receptors called nucleotide oligomerization domain (NOD)-like rece...

Varicocele is primarily tortuous dilation of the internal spermatic vein [ISV] and pampiniform plexus in scrotum. It’s most common correctable cause infertility. It has a higher prevalence primary secondary infertility men. In this article, we reviewed advantages disadvantages microscopic intermediate sub inguinal [MISV] varicocelectomies over conventional surgical methods. Although various mec...

background: the nutcracker syndrome represents a clinical condition caused by compression of the left renal vein (lrv) between the superior mesenteric artery (sma) and the aorta. one of its manifestations is left-sided varicocele. the aim of this study is to determine the prevalence of nutcracker syndrome in patients with primary and recurrent high grade left-sided varicocele.   methods: fifty ...

introduction: perepubertal varicocele can result in hypotrophy of testes, sperm damage and decrease the function of leydig cells in future. pathophysiology of varicocele is unclear. increased reactive oxygen species (ros) is a major theory. there are many controversies in treatment of pediatric varicocele. flaxseed (fs) is the richest source of lignans with antioxidant properties. the aim of th...

background: reactive oxygen species (ros) are a group of free radicals that in excessive amounts have negative influence on sperm quality and function. objective: to study the effect of varicocele and its severity on the level of ros in infertile men with clinical varicocele. materials and methods: in this controlled prospective study, 42 men with clinically diagnosed left varicocele and 30 fer...

The aim of this study was to assess the level of malondialdehyde (MDA) in the seminal plasma of infertile men and to highlight a relationship between the level of MDA and semen parameters. Eighty-one infertile patients were divided into groups according to their clinical diagnosis: genitourinary infections, varicocele and idiopathic infertility. Semen quality was assessed by light and transmiss...