Whole-slide images (WSI) have acquired a stable place in diagnostic histopathology and immunohistochemistry. Immunofluorescence (IF) techniques hold a limited and selective role in diagnostics (eg, renal and cutaneous pathology) and so far remain excluded from the digital pathology evolution, with notable exceptions, such as quantitative immunopathology. We explored the ability of a commercial ...

Background:  Hydrogen has been demonstrated can selectively reduce the hydroxyl, which is the main cause of ionizing radiation-induced damage. Amifostine (AM) is the only radioprotective drug approved by the U.S. Food and Drug Administration for use in radiotherapy. The purpose of the present study was to investigate the combined radio-protective effect of hydrogen rich water (HRW) and AM....

RATIONALE Human skin contains photolabile nitric oxide derivates like nitrite and S-nitroso thiols, which after UVA irradiation, decompose and lead to the formation of vasoactive NO. OBJECTIVE Here, we investigated whether whole body UVA irradiation influences the blood pressure of healthy volunteers because of cutaneous nonenzymatic NO formation. METHODS AND RESULTS As detected by chemolum...

1 Laboratory of Experimental Psychology and Neuroscience (LPEN), Institute of Cognitive Neurology, Favaloro University, Buenos Aires, Argentina 2 Institute of Neuroscience, Favaloro University, Buenos Aires, Argentina 3 National Scientific and Technical Research Council, Buenos Aires, Argentina 4 Laboratory of Cognitive and Social Neuroscience, Universidad Diego Portales, Santiago, Chile *Corre...

Geometric and densitometric properties of the Barr body of early and late phase II confluent human fibroblasts are analysed by the automated image analyser Quantimet 720 D. In cells with the same 2C DNA content, the state of condensation of the Barr body varies proportionally wih the state of condensation of the entire nucleus yielding a correlation between nuclear and Barr body area. In light ...

BALB/c mice were inoculated subcutaneously with 10(6) cells from either of two syngeneic sarcomas 1315 and 1425. 6--8 days later, the mice were randomized into groups which were left untreated or given 400 rads of whole body irradiation. Irradiation significantly retarded the growth of both sarcomas, and complete regressions were seen of approximately equal to 30% of the small, established 1315...

We designed a modified transpalatal arch (tongue anchorage pad, TAP) to help control the vertical dimension. This study aimed to evaluate its efficiency by measuring the tongue resting pressure at different anteroposterior positions of the TAP in the upright and supine positions and to investigate the effect of changes in body position. Our study recruited 17 volunteers with individual normal o...

background:  hydrogen has been demonstrated can selectively reduce the hydroxyl, which is the main cause of ionizing radiation-induced damage. amifostine (am) is the only radioprotective drug approved by the u.s. food and drug administration for use in radiotherapy. the purpose of the present study was to investigate the combined radio-protective effect of hydrogen rich water (hrw) and am. mate...

Introduction: Total body irradiation (TBI) is a form of external beam radiotherapy which is used in conjunction with chemotherapy with the purpose of immunosuppression. Since the target in TBI is the whole body so a uniform dose distribution throughout the entire body during TBI is necessary. As recommended by AAPM dose variation must be within ±10% of prescription dose. A revi...