Targeted glycoproteomics is an effective way to discover disease-associated glycoproteins in proteomics and serial affinity chromatography (SAC) using lectin and glycan-targeting antibodies shows glycan diversity on the captured glycoproteins. This study suggests a way to determine glycan heterogeneity and structural analysis on the post-translationally modified proteins through serial affinity...

The most common mechanism of blunt thoracic trauma is an MVC, followed by falls, assaults, and crush injuries. Compressive forces directly injure the thoracic cage and underlying viscera and result in rib fractures and pulmonary contusion. Deceleration produces traction on fixed structures such as the isthmus of the aorta and the carina and results in traumatic aortic and tracheobronchial injur...

Barley, Hordeum vulgare L., is the most important crop in Finland based on cultivated land area. Net blotch, a disease caused by Pyrenophora teres Drech., is the most damaging disease of barley in Finland but is also important in other barley cultivating areas. The pressure to improve the economics and efficiency of agriculture has increased the need for more efficient plant protection methods....

Road safety is a very important issue in many jurisdictions. Road collisions, which have been identified as a major public health problem by the World Health Organization, are the 11th leading cause of global deaths.1 This problem is being addressed in North America through improved education, enforcement and engineering. Having access to better information systems and tools to support decision...

Organic anion transporting polypeptides (rodents, Oatps; human, OATPs) are primarily involved in the transmembrane transportation of a wide range of endogenous and exogenous compounds. Multiple mouse Oatp1 isoforms are closely located on chromosome 6, where each isoform shows distinct tissue distribution; Oatp1b2, Oatp1a6, and Oatp1c1 are expressed exclusively in the liver, kidney, and cerebrum...