For roughly 25 years, 125I and 103Pd sources have been used in the treatment of various malignant diseases such as prostate cancer. Various new sources have been marketed and produced to meet the demand for new sources to use in treatment. Recently, IsoAID LLC created the ADVANTAGE 103Pd source. Various dosimetric parameters must be determined to facilitate treatment planning using this source....

Background: Due to interesting tumor imaging properties of bis-thiosemicarbazones, [103Pd]-di-acetyl-bis (N4-methylthiosemicarbazone) ([103Pd] ATSM2) was prepared according to the analogy of radio copper homologues. Materials and Methods: Palladium-103 (T1/2=16.96 d) was produced via the 103Rh (p,n) 103Pd nuclear reaction with proton energy 18 MeV. The final activity was eluted in form of Pd ...

Background: Palladium-103 (103Pd) is a brachytherapy source for cancer treatment. The Monte Carlo codes are usually applied for dose distribution and effect of shieldings. Monte Carlo calculation of dose distribution in water phantom due to a MED3633 103Pd source is presented in this work. Materials and Methods: The dose distribution around the 103Pd Model MED3633 located in the center of 30×...

Background: A new treatment approach for most patients who have undergone early stage non-small-cell lung carcinoma (NSCLC), is wedge resection plus permanent implant brachytherapy. However, the specification of dose to medium at low energies especially in heterogeneous lung is unclear yet.Objective: The present study aims to modify source strength for different configurations of 125I and 103...

Theoretical and experimental dosimetric studies have been supplied useful information on the dependence of the brachytherapy source geometry and materials (1-5). Usually, Monte Carlo method is used to define dose distribution function, the radial dose variation, and the dose calculation close to the source in brachytherapy. Chen et al. (6). calculated the distribution of absorbed dose around co...

background: palladium-103 (103pd) is a brachytherapy source for cancer treatment. the monte carlo codes are usually applied for dose distribution and effect of shieldings. monte carlo calculation of dose distribution in water phantom due to a med3633 103pd source is presented in this work. materials and methods: the dose distribution around the 103pd model med3633 located in the center of 30×30...

In the recommendations of Task Group #43 from American Association of Physicists in Medicine (AAPM TG43), methods of brachytherapy source dosimetry are recommended, under full scattering conditions. However, in actual brachytherapy procedures, sources may not be surrounded by full scattering tissue in all directions. Clinical examples include high-dose-rate (HDR) brachytherapy of the breast or ...

In 2001, the use of cylindrical coordinates was demonstrated to be more suitable than was the use of polar coordinates for accurate computer calculations during treatment planning for 192Ir intravascular brachytherapy sources. In the present work, we investigated the applicability of cylindrical coordinate-based TG-43U1 parameters for dosimetric evaluation and dose calculations for RadioCoil 10...

Objective: Brachytherapy sources are widely used for the treatment of cancer. The report of Task Group No. 43 (TG-43) of American Association of Physicists in Medicine is known as the most common method for the determination of dosimetric parameters for brachytherapy sources. The aim of this study is to obtain TG-43 dosimetric parameters for 60Co, 137Cs, 192Ir and 103Pd brachyt...

background: due to interesting tumor imaging properties of bis-thiosemicarbazones, [103pd]-di-acetyl-bis (n4-methylthiosemicarbazone) ([103pd] atsm2) was prepared according to the analogy of radio copper homologues. materials and methods: palladium-103 (t1/2=16.96 d) was produced via the 103rh (p,n) 103pd nuclear reaction with proton energy 18 mev. the final activity was eluted in form of pd (n...