Cytochrome P450 (P450) function requires the interaction of P450 and NADPH-cytochrome P450 reductase (CPR) in membranes, and is frequently studied using reconstituted systems composed solely of phosphatidylcholine. There is increasing evidence that other endoplasmic reticulum (ER) lipids can affect P450 structure, activity, and interactions with CPR. Some of these lipid effects have been attrib...

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Cette belle edition bilingue d’un manuscrit compose entre 1905 et 1913 permet de decouvrir la vie l’œuvre du paysan barde breton Julien Godest (1849-1933). On peut faire un parallele ce texte – son auteur Jean-Marie Deguignet (1834-1905), dont le Histoire ma vie, ecrit 1898 1905, a connu immense succes lorsqu’il ete publie en 1998 sous titre Memoires bas-breton. Les deux hommes ont grandi dans ...

BACKGROUND The number of centenarians has increased rapidly since the 1950s. In Denmark, 42% more of the 1905 birth cohort made it to 100 years of age compared to the 1895 cohort. We tested whether this increased survival proportion has resulted in an increased disability level in the more recent cohort of centenarians. METHODS The Longitudinal Study of Danish Centenarians (LSDC) included all...

In the history of international conflicts, common cause that becomes trigger is expansion hegemony. One conflicts recorded due to hegemony area occurred between Japan and Russia, which began in second half 19th century continued until beginning 20th century. The conflict heated up succeeded triggering an open war two countries. ended with signing Portsmouth agreement on 5 September 1905, as vic...