Wickham Chen, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected] Cheng-An Yang, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1641. Fax: 214-768-4095. Email: [email protected] Junheng Zhang, Southern Methodist University, Dallas, TX, 75275. Phone: 214-768-1402. Fax: 214-768-3573. Email: [email protected]...

Radiotherapy, a therapeutic modality of cancer treatment, nonselectively damages normal tissues as well as tumor tissues. The search is ongoing for therapeutic agents that selectively reduce radiation-induced normal tissue injury without reducing tumoricidal effect, thereby increasing the therapeutic ratioof radiation therapy. Our laboratory established 5-(4-methylpiperazin-1-yl)2-[2ʹ-(3,4-dime...

Blow flies of the genus Hypopygiopsis are considered forensically important. In Thailand, four Hypopygiopsis species coexist, i.e., Hypopygiopsis fumipennis, Hypopygiopsis infumata, Hypopygiopsis violacea and Hypopygiopsis tumrasvini. In this study, the ontogeny and developmental rate of H. tumrasvini eggs, larvae and pupae were determined in the laboratory chamber reared at 25.0±2.0°C and 80.0...

In this issue of Rheumatology, Gaujoux-Viala et al. [1] studied a cohort (ESPOIR) with early rheumatoid arthritis (ERA) where 813 patients were followed up for more than 2 years and rated their quality of life (QoL). This valuable study demonstrates that initially 11% and later 3.3% have a utility that is worse than death, which translates as death being a better quality of life than their curr...

Averaging is often used in ordinary differential equations when dealing with fast periodic phenomena. It is shown here that it can be used efficiently in optimal control. As the period tends to zero, a limit or "averaged" problem is defined. The open loop optimal control of the limit problem induces a cost which is optimal up to the second order when evaluated through the original dynamics. The...

RASopathies are developmental disorders caused by germline mutations in the Ras-MAPK pathway, and are characterized by a broad spectrum of functional and morphological abnormalities. The high incidence of these disorders (∼1/1000 births) motivates the development of systematic approaches for theirefficient diagnosis and potential treatment. Recent advances in genome sequencing have greatly faci...

Introducción: la ultrasonografía endoscópica (USE) ha demostrado ya su utilidad en la evaluación de las lesiones submucosas, en la estadificación del cáncer digestivo en general, y del linfoma gástrico tipo MALT en particular. El objetivo de este trabajo fue la estadificación por USE. Pacientes y método: veinticuatro enfermos (10 mujeres y 14 varones) con edad media de 56 años y con posible lin...

MicroRNAs (miRNAs) are key regulators of multiple cancers, including non-small cell lung carcinoma (NSCLC). The aim of this study was to determine the expression pattern of miR-769-5p in NSCLC and to investigate its biological role during tumorigenesis. We showed that miR-769-5p was significantly downregulated and predicted poor prognosis in NSCLC compared with corresponding normal tissues. We ...

The advancement of transmission techniques provides simplicity and comfort in health monitoring, specifically in identifying the health conditions of each individual. ECG signal processing systems are the most efficient diagnostic applications of health care monitoring systems. In practical applications we use ECG signal processing systems in hospitals to monitor the vital signs of patients and...