Superficial acral fibromyxoma is a benign and slow-growing solitary soft-tissue neoplasm. Since being described in 2001, more than 100 cases of superficial acral fibromyxoma on the foot have been reported worldwide, none of which have been reported in the podiatric medical literature. Only nine cases of superficial acral fibromyxoma have been reported with presentation on the plantar heel. We r...

99 Indian Journal of Dermatology 2016; 61(1) 2. Abdallah MA, Ghozzi MY, Monib HA, Hafez AM, Hiatt KM, Smoller BR, et al. Necrolytic acral erythema: A cutaneous sign of hepatitis C virus infection. J Am Acad Dermatol 2005;53:247‐51. 3. Khanna VJ, Shieh S, Benjamin J, Somach S, Zaim MT, Dorner W Jr, et al. Necrolytic acral erythema associated with hepatitis C: Effective treatment with interferon ...

Acral melanoma is a rare melanoma subtype with distinct epidemiological, clinical and genetic features. To determine if acral melanoma cell lines are representative of this melanoma subtype, six lines were analysed by whole-exome sequencing and array comparative genomic hybridisation. We demonstrate that the cell lines display a mutation rate that is comparable to that of published primary and ...

study in Japan. Arch Dermatol. 2004;140(10):1233-1238. 6. Altamura D, Zalaudek I, Sera F, et al. Dermoscopic changes in acral melanocytic nevi during digital follow-up. Arch Dermatol. 2007;143(11):13721376. 7. Ozdemir F, Karaarslan IK, Akalin T. Variations in the dermoscopic features of acquired acral melanocytic nevi. Arch Dermatol. 2007;143(11):13781384. 8. Minagawa A, Koga H, Saida T. Dermos...

BACKGROUND The role of the phosphatidylinositol-3 kinase signaling pathway in the development of acral melanoma has recently gained evidence. Phosphatase and tensin homologue (PTEN), one of the key molecules in the pathway, acts as a tumor suppressor through either an Akt-dependent or Akt-independent pathway. Akt accelerates degradation of p53. OBJECTIVE We assessed the expression of PTEN, ph...

Although exposure to the sun is recognized as the principal factor in the genesis of melanoma, this tumor also arises in areas of the skin not generally exposed to the sun, as is the case in acral lentiginous melanoma of the sole, in which the role of UV radiation would appear insignificant. Acral melanomas account for 2% of all melanomas (1.5% for plantar acral melanoma), with an incidence of ...

PURPOSE A retrospective study was conducted to review the treatment and outcomes of mainly melanomas in acral location in a single institution in Korea, and to evaluate the prognostic significance of anatomic locations of the tumor. MATERIALS AND METHODS A retrospective review was completed on 40 patients between 2001 and 2006 to obtain pertinent demographic data, tumor data, treatment charac...

BACKGROUND Melanocytic nevi are frequently found on acral volar skin. Differentiation between nevi and melanoma is essential and sometimes difficult, although dermoscopy has enabled a more specific diagnosis of pigmented lesions. Dermoscopic patterns of lesions on acral volar skin have mostly been described in European and Asian populations. The Latin American population is heterogeneous, and p...