Saffron (Crocus sativus L.) has been considered as a medicinal plant since ancient times and also widely used as food additive for its color, taste and odor. The pharmacological properties of saffron and its main constituents, crocin and safranal have been evaluated using different in vivo and in vitro models. Additionally, other lines of studies have found toxicological effects of saffron.  Ho...

Background: Trachyspermum ammi is one of the prominent plant in traditional medicine of the east with several medicinal effects such as improvement of stomach disease, digestive disorder, diarrhea, hemorrhoid, bladder stones, respiratory disease and etc. Medicinal plants is one of the important reason of toxicity particularly in children and the elderly therefore, evaluation of the toxic effect...

persea americana is a plant used by traditional medicine practitioners to treat ailments including diarrhoea and diabetes mellitus in nigeria. hence, the chloroform and the methanol fractions of the chloroform-methanol extract of the leaves of p. americana were evaluated for their acute toxicity as well as anti-diarrhoeal effects in wistar rats to substantiate this claim. the chloroform and met...

in this study, cadmium (cd) accumulation was studied in an experimental aquatic exposure. mosquitofish (gambusia affinis) were acutely exposed for 96 h to a high concentration of cd (12 mg/l) and were chronically exposed to a low concentration of cd(0.4 mg/l) for 30 days. cd accumulation profiles differed between the two cd exposures. the cd concentation in g. affinis tissues increased linearly...

Atrazine is currently the most widely used herbicide in agriculture for the production of corn and other crops in the world. In the present research, the effect of acute and chronic toxicity of atrazine (herbicide) on blood biochemical indices of grass carp (Ctenopharhyngoden idella) an important species of commercial fish was studied. In acute toxicity, pollutant toxicity to fish was tested by...

Berberis vulgaris and berberine, its main component, traditionally have been used for treatment of various disorders. The pharmacological properties of them have been investigated using different in vivo and in vitro models. In spite of beneficial effects of B. vulgaris on different cell lines, there are documents have revealed negative impacts of it on animal and human. In this regards, the de...

in this study, cadmium (cd) accumulation was studied in an experimental aquatic exposure. mosquitofish (gambusia affinis) were acutely exposed for 96 h to a high concentration of cd (12 mg/l) and were chronically exposed to a low concentration of cd(0.4 mg/l) for 30 days. cd accumulation profiles differed between the two cd exposures. the cd concentation in g. affinis tissues increased linearly...

normal 0 false false false en-us x-none ar-sa background: acute kidney injury (aki) is commonly occurred in intensive care unit (icu) patients. the aim of the study was a comparison of rifle (risk of renal injury/injury to the kidney/failure of kidney function/loss of kidney function/end stage disease) classification with other scoring systems in the evaluation of aki in icus. materials and met...