We show that fluorescence lifetime is a powerful contrast mechanism that can enhance the whole-body imaging of fluorescent proteins (FPs), in the presence of background tissue autofluorescence (AF). The nonexponential AF decay is characterized from time-domain (TD) measurements on multiple nude mice and separated from the FP fluorescence using a linear fit to a priori basis functions. We illust...

Metastasis of gastroesphageal junction (GEJ) adenocarcinoma in skeletal muscle is rare and primary sites for skeletal muscle metastases are usually lung, renal and colorectal cancer. We have encountered with the first case report of solitary psoas muscle metastasis of GEJ adenocarcinoma. Here we describe a 65 years old man was diagnosed with GEJ adenocarcinoma in tertiary hospital, Tehran, Iran...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

a 70 year old male presented with right lower quadrant pain and anorexia for about 72 hours prior to hospital admission. he underwent laparotomy with impression of acute appendicitis. the operative finding was an inflamed tumoral appendix without appendicular base involvement, and appendectomy was done. the patient had an uneventful post-op course. due to the pathology report of prostatic carci...

There is currently no effective biomarker for determining the survival of patients with lung adenocarcinoma. The purpose of the present study was to construct a prognostic survival model using microRNA (miRNA) expression data from patients with lung adenocarcinoma. miRNA data were obtained from The Cancer Genome Atlas, and patients with lung adenocarcinoma were divided into either the training ...

This study was conducted to confirm the hypothesis that intestinal microflora are required for the development of adenocarcinoma in the colon of the TCRb and p53 double-knockout (TCRb p53) mouse. Germ-free TCRb p53 mice were produced. At 7 weeks of age, the animals were divided into two groups (n 5 10/group), and one of these groups was conventionalized. Animals of both groups were subjected to...

although most breast cancers are adenocarcinomas of the mammary gland, primary breast sarcomas may also arise from mammary gland mesenchymal tissue. sarcomas represent less than 1% of primary breast neoplasms. these tumors are at high risk of recurrence and are known to have poor prognosis. surgical resection is the primary treatment for these lesions and axillary lymph node dissection is not r...

background and objectives: to compare pathologic complete response (pcr) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (nact) by 5-fu or xeloda (capecitabine) with and without eloxatin (oxaloplatin injection). materials and methods: seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. two basic chemotherapy regi...

This study was conducted to confirm the hypothesis that intestinal microflora are required for the development of adenocarcinoma in the colon of the TCRbeta and p53 double-knockout (TCRbeta-/- p53-/-) mouse. Germ-free TCRbeta-/- p53-/- mice were produced. At 7 weeks of age, the animals were divided into two groups (n = 10/group), and one of these groups was conventionalized. Animals of both gro...