background : breast cancer is a complicated disease and has various clinical manifestations and prognosis. the aim of this study is to make a breast cancer model suitable for basic, preclinical and clinical studies. materials and methods: five virgin bulb/c mice aged 6 weeks and spontaneous murine mammary adenocarcinoma cells (mmac) were used. after anesthesia induction, 1-3 million of mmacs we...

objective: to evaluate the potentiality of ovcar–3 cell line of ovarian adenocarcinoma as a xenograft model for ovarian adenocarcinoma in nude mice. materials and methods: the cell line isolated from advanced human ovarian adenocarcinoma, were inoculated to eight nude mice and two months later. established tumors were transferred to pathology laboratory to be prepared by h&e; staining and immun...

abstract background and purposes: gastrointestinal cancers including stomach adenocarcinoma are very prevalent and one the main causes of death due to cancer. mazandaran has a high mortality rate of stomach adenocarcinoma. this study was proposed for estimation of survival time in patients with stomach adenocarcinoma. materials and methods: the study was historical cohort. the samples were the ...

Objective(s): Studies have indicated advantageous properties of [DOTA-DPhe1 , Tyr3 ] octreotide (DOTATOC) in tumor models and labeling with gallium. Breast cancer is the second leading cause of cancer mortality in women, and most of these cancers are often an adenocarcinoma. Due to the importance of target to non-target ratios in the efficacy of diagnosis, the pharmacokinetic of 68Ga-DOTATOC in...

background: one million people are diagnosed with gastric cancer (gc) annually and the prognosis for patients with advanced gc or gastroesophageal junction (gej) cancer is usually poor with a median survival time of 8 to 10 months. recent reports have identified that anti her2 target therapy improved the median survival rate in patients with her2 positive gc; but a wide range of her2 overexpres...

background: the oncologic behavior of mucinous adenocarcinoma (ma) of colorectal differs from non-mucinous adenocarcinoma (nma). ma is more advanced at diagnosis and has a poorer prognosis than nma. we aimed to evaluate prognostic factors and survival rate in patients with ma compared with nma in western iran. methods: during 2008-2015 in a retrospective study, 83 patients with crc referred to ...

background: gastric cancer is the second leading cause of cancer death. the aim of this study was to determine the survival rate affected by risk factors in patients with gastric adenocarcinoma. methods: we performed this retrospective cohort study on patients diagnosed with gastric adenocarcinoma during 2005-2012 in hamadan, iran. all patients with pathological diagnosis enrolled in the study....

the patient was a 22-year-old female with ataxia-telangiectasia presented with progressive dysphagia to solid food from 2 months ego. she had lost 17 kg in that period. physical findings were cachexia, telangiectasias of sclera, ataxia in limbs movements and epigastric tenderness.there was a tumoral lesion in gastric lesser curvature with extension to esophagogastric junction in endoscopy. path...

Alpha-fetoprotein (AFP) producing gastric adenocarcinoma is considered as a rare subtype of gastric adenocarcinoma. Compared with AFP non-producing gastric adenocarcinoma, our study and other previous studies showed that AFP producing gastric adenocarcinoma is more aggressive and prone to liver metastasis. Using the Protein Pathway Array, 11 of out of 286 proteins tested were found to be differ...