Objective: To compare the efficacy and safety of transcervical foley catheter alone to transcervical foley catheter with extra-amniotic saline infusion for labour induction and cervical ripening in women with an unfavourable cervix. Method: 100 pregnant women (study population) were allocated randomly into two groups. First 50 patients were assigned to treatment with transcervical foley cathete...

BACKGROUND Induction of labour is the intentional initiation of cervical ripening and uterine contraction for the purpose of accomplishing delivery, prior to onset of spontaneous parturition. This study was conducted to compare maternal and neonatal outcome in women induced with Prostaglandin E2 gel, Prostaglandin E2 pessary and extra-amniotic saline infusion with oxytocin at Bishops score < 5....

A randomized controlled trial was performed to compare the efficacy of extra-amniotic saline infusion (EASI) and intracervical traction with a Foley catheter for pregnancy termination. The study population consisted of 200 women with a pregnancy duration of 14 to 28 weeks and an indication for pregnancy termination. Inclusion criteria were an absence of effective uterine contractions, intact me...

Previous research has shown that injection of morphine into the ventral tegmental area (VTA) facilitates the onset of maternal behavior in virgin female rats, and injection of the opioid antagonist naltrexone into the VTA disrupts the onset of maternal behavior in parturient rats. Placentophagia -- ingestion of placenta and amniotic fluid, usually at parturition -- modifies central opioid proce...

OBJECTIVE The aim of this study is to further compare the efficacy of PGE2 suppository, the intracervical foley catheter and extra-amniotic saline infusion in nulliparous women referred for labor induction. MATERIALS AND METHODS Totally 368 nulliparous women with a Bishop score ≤ 4 with singleton gestation, vertex presentation and intact membrane referred for labor induction were randomly ass...

Six fetal sheep were operated on at 118 to 121 days of gestation. The pulmonary end of the trachea was connected to the gastric end of the esophagus with a section of tubing. This left urine as the only source of amniotic fluid and intramembranous absorption as sole exit. Multiple indwelling fetal vascular, intra-amniotic, allantoic, and a fetal bladder catheter were placed. Beginning 5 days af...

BACKGROUND Early events leading to intrauterine infection and fetal lung injury remain poorly defined, but may hold the key to preventing neonatal and adult chronic lung disease. Our objective was to establish a nonhuman primate model of an early stage of chorioamnionitis in order to determine the time course and mechanisms of fetal lung injury in utero. METHODOLOGY/PRINCIPAL FINDINGS Ten chr...