A NUMBERof drugs have been employed in an attempt to increase the mental capacity of oligophrenics. The effect of thiamine on learning demonstrated by Harrell (1943, 1946) led Rudolf (1949, 1950) to use this vitamin in the treatment of oligophrenia. Similarly, the early studies of Zimmermann and Ross (1944) on glutamic acid resulted in a large number of papers on its debatable effect in feeblem...

29 29 GENERIC NAME PAGE Amphetamine 350 Caffeine 351 Doxapram 349 Fenfluramine 351 Methamphetamine 350 Methylphenidate 350 Modafenil 351 GENERIC NAME PAGE Pemoline 350 Pentylenetetrazol 349 Sibutramine 351 Phentermine 351 Theobromine 351 Theophylline 351 Central nervous system (CNS) stimulation is the primary action of a diverse group of pharmacological agents and an adverse effect associated w...

Cardiac asystole which manifests itself as a ventricular fibrillation or cardiac standstill is an accident occurring in approximately 0.1 per cent of all surgical interventions.’ It has been reported that 87 per cent of cardiac arrests occur in the operating room.6 In many medical institutions of the world, the customary approach to the problem is time consuming and conservative. All too freque...

Sir, Costa and his colleagues {QJ Med 1995; 88:767-73) are to be congratulated for providing more information about chronic fatigue syndrome. Hypocapnia is a powerful and readily available cerebral vasoconstrictor. 1 The 'cerebral vasoconstric-tion, and reduction in cerebral blood flow, are initiated when the arterial pCO 2 has fallen 2 mmHg below normal. When the pCO 2 has fallen by 25 mmHg, c...