conclusions based on existing data, hiv infection surveillance, performance of standard precaution, and post exposure prophylaxis with anti-retroviral drugs outlined in this review article represent reasonable interim approaches to this complex problem. context human immunodeficiency virus (hiv) infection and acquired immunodeficiency syndrome (aids) concentrated in injecting drug users (idus) ...

introduction: intravenous drug users as a serious health problem in communities have economical and social effects as well as health and hygienic complications. viral infections may be transmitted through drug injection by shared syringes among users. the aim of this study has been to determine the relative frequency of hbv, hcv and hiv infection’s markers as epidemiological data in ahvaz. mate...

Background: During the recent years, significant progress has been achieved on development of novel anti-viral drugs. Natural products are assumed as the potential sources of novel anti-viral drugs; therefore, there are some previous studies reporting the anti-viral compounds from venomous animals. Based on the significant value for tracing of non-toxic anti-viral agents from natural resources,...

previously, we reported that the kaempferol and kaempferol-7- o -glucoside isolated from securigera securidaca showed potent anti-hsv activity. in the present study the anti-hiv-1 activities of kaempferol and kaempferol-7- o -glucoside are investigated at different concentrations (100, 50, 25 and 10 µg/ml) using hiv-1 p24 antigen kit. real-time polymerase chain reaction (rt-pcr) assay was also ...

this study was planned to determine hiv seroprevalence among pulmonary tuberculosis patients, to characterize the isolated mycobacteria into typical and atypical strains and to evaluate the drug resistant pattern of mycobacterial isolates. the study aims to correlate multidrug resistance (mdr) and hiv seropositivity status in pulmonary tuberculosis patients. during the year 1994-1997, 750 pulmo...

background: beside various factors for producing diabetes, it seems that chronic hepatitis c, hiv/hcv co-infection, and anti-retroviral treatment especially including protease inhibitors may predispose to diabetes. this study conducted to determine prevalence of diabetes in hiv and hcv patients. methods: the registries of 150 hcv patients, 50 hiv patients and 90 hiv/hcv co-infected patients in ...

background: during the recent years, significant progress has been achieved on development of novel anti-viral drugs. natural products are assumed as the potential sources of novel anti-viral drugs; therefore, there are some previous studies reporting the anti-viral compounds from venomous animals. based on the significant value for tracing of non-toxic anti-viral agents from natural resources,...

ANTI-HIV DRUG TARGETS HIV is a retrovirus, with a simple structure described in Box 1, and illustrated in Figure 1. It contains genes coding for a number of unique viral enzymes, required at different stages of the virus’s life cycle (see Box 2 and Figure 2). One of these is reverse transcriptase, required to make copies of the viral genes once it has infected human cells. Another is HIV protea...

injection drug use has been the most growing rout of drug abuse in iran in the past decade and it has been responsible for the transmission of hiv virus in more than two third of cases. the aim of the present study was to determine the prevalence of hiv and hepatitis b in a group of idu cadavers and to compare the results to a group of cadavers of the normal population. in a case-control study ...