Background and objectives: Thegenus Centaurea from the Asteraceae family is one of the most widely distributed plant genera worldwide that has been extensively used in folk medicine for hundreds of years. The present study is the first investigation about the principal constituents of Centaurea albonitens Turrill which is native to Iran. Methods: </str...

Phytoestrogens are defined as plant-derived compounds with estrogen-like activities according to their chemical structures and activities. Plant lignans are generally categorized as phytoestrogens. It was reported that (-)-arctigenin, the aglycone of arctiin, was demethylated to (-)-dihydroxyenterolactone (DHENL) by Eubacterium (E.) sp. ARC-2. Through stepwise demethylation, E. sp. ARC-2 produc...