background wound healing is a dynamic process with inflammatory response and oxidative reaction in the damaged area. alpha ointment (ao) and arnebia euchroma (arnebia) are herbal medicines with antioxidant and anti-inflammatory effects that can be used as wound healing agents. ao is a commonly used ointment while arnebia is a newly introduced one. objectives we aimed to compare the effects of a...

background: there is a growing demand for mass production of shikalkin (a natural pigment consisted of shikonin and alkannin) due to its increasing applications in cosmetics, pharmaceutical and nutrition industries. the root of iranian arnebia euchroma produces shikalkin. the promising capability of this plant for shikalkin production has already been demonstrated in cell culture studies. objec...

Objective: The present study aimed to the isolation and characterization of phytochemicals from tissue cultures of Arnebia hispidissima. The isolated compounds were evaluated for their antioxidant and antimicrobial activities. Materials and Methods: Six derivatives of alkannin and shikonin were isolated and characterized by using various physical and spectroscopic techniques from callus tissue ...

background: obesity is a worldwide health problem which is associated with a lot of complications. one of these comorbidities is the metabolic syndrome that is in correlation with abdominal fat thickness and waist circumference. various methods were used to reduce abdominal fat thickness such as liposuction. a noninvasive method is the topical agent. in this study, we investigated the effective...

Arnebia euchroma is from Boraginaceae family. Various therapeutic effects have been reported for different species of this plant. The aim of this study was to investigate antioxidant activity of hydroalcoholic extract of the root of A. euchroma and its protective effect on hepatotoxicity induced by CCl4 in mice. In this experimental study, A. euchroma was extracted with ethanol solvent by macer...

Suspension cultures of Arnebia euchroma supported with liquid perfluorodecalin (PFD) degassed, aerated, or ethylene-saturated were investigated as a novel in situ extraction system for enhanced alkannin/shikonin production. Simultaneously, the effect of PFD applied as the liquid gas carrier on the growth of A. euchroma biomass was studied. The similar dry (4-fold) and fresh (7-fold) biomass inc...

Nitrogen (N) strongly affects plant growth and metabolism. Although ammonium toxicity has been reported, the effects of nitrogen on shikonin biosynthesis remain obscure. In this study, we tested four different concentrations NH4+ Arnebia euchroma hairy roots (AEHR) to clarify influence AEHR accumulation in them possible mechanisms. The results showed that compared with 0% treatment (only nitrat...