Mohammad Azadbakht
Traditional and Complementary Medicine Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran
[ 1 ] - Effect of Malva sylvestris cream on burn injury and wounds in rats
Objectives: Burn injury is one of the most health-threatening problems in the world. Malva sylvestris (M. sylvestris) flowershave a high mucilage content and are used as a remedy for cut wound and dermal infected wounds in Iranian folklore Medicine. The purpose of this study was to investigate the effect of M. sylvestris cream on the second degree burn injury in rats. Materials and Methods: Fiv...
[ 2 ] - بررسی تطبیقی خواص خاکشی از منظر دانشمندان طب سنتی با پژوهشهای پزشکی معاصر
Introduction: Due to the prevalent usage of flixweed among people, the aim of this research was a comparative study on the properties of flixweed from the perspective of traditional and modern medicine scientists. Methods: This study was carried out by the use of traditional medicine reference books such as Al-Qanon, Al-Hawi, Makhzanol Aladvyh, Alsydnh fi Tibb. The key words for traditio...
[ 3 ] - فیتواستروژن‌ها (Phytoestrogens)
مطالعات اپیدمیولوژی پیشنهاد میکند جوامعی که مصرف کننده زیاد فیتواستروژن‌ها در رژیم غذایی خودشان هستند از ریسک پایینتری نسبت به خیلی از بیماری‌ها که به بیماری غربی موسوم هستند برخوردار هستند. فیتواستروژن‌ها در خیلی از غذاها وجود دارند و فعالیت بیولوژیکی آنها در حیوانات در مطالعات متعددی به اثبات رسیده است. فیتواستروژن‌ها شامل چندین گروه از ترکیبات می‌شوند از جمله لیگنان‌ها، ایزوفلاونوییدها، ک...
[ 4 ] - تمایز سلول های بنیادی مزانشیمال به سلول های تولید کننده انسولین توسط گیاه والک کوهی و خار مریم
Background and purpose: Today, increased rate of demand for insulin is predictable due to increasing cases of diabetics in the world. Therefore, it is necessary to develop economic approaches and increasing the production of insulin for the future and medicinal plants could be regarded as a promising prospect for insulin production. Materials and methods: The Allium ursinum and Silybum marianu...
[ 5 ] - بررسی اثر مخلوط پودر دانه شنبلیله، ریزوم زنجبیل و مان ترنجبین بر قدرت عضلانی و ترکیب بدنی ورزشکاران
Background and purpose: In recent years, consumption of commercial protein supplements and hormones that improve body appearance endangers the health of athletes especially in bodybuilding sport. Recently, use of plant extracts to reduce the side effects of drugs and improving physical activity has gained a lot of attention. The aim of this study was to investigate the effect of a supplement (m...
[ 6 ] - اثر اشتهاآوری فرآورده حاوی عصاره گل سپاس ( Gentiana olivieri )در کودکان مبتلا به بی اشتهایی
Background and purpose: Gentiana olivieri Griseb is a famous species in Gentianaceae family. G. olivieri is native to Iran, and grows mainly in the western regions of the Zagros Mountains. Thinking over the importance of proper nutrition in child’s growth and lack of proper appetizer in pharmaceutical market, preparing an effective herbal product was considered to increase appetite in childre...
[ 7 ] - بررسی اثر فراکسیون‌های عصاره میوه گیاه سرو کوهی (Juniperus communis) بر انحلال سنگ‌های ادراری به صورت برون تنی
Background and purpose: Urolithiasis is one of the most common diseases of urinary tract. Abdominal colic pain, nausea and vomiting, and hematuria are the major clinical complains. Renal stones may obstruct urinary tract, and then damage the kidney. Medical treatment, removing the stones by extracorporeal shock wave lithotripsy, percutaneous lithotripsy, and ureteroscopic lithotripsy are common...
[ 8 ] - داروهای گیاهی 5 ضد تک یاخته شایع
According to the statistics provided by the World Health Organization (WHO), about 80% of the world population nowadays uses herbal drugs for treatment of diseases. Natural products obtained from medicinal plants, serve as a great source for drug production and are the main basis of new drug compounds. Unicellular organisms (Protozoa) are the cause of deaths and spread of diseases in vario...
[ 9 ] - The hepatoprotective effect of Arnebia euchroma hydro-alcoholic extract against liver toxicity induced by CCl4 in mice
Arnebia euchroma is from Boraginaceae family. Various therapeutic effects have been reported for different species of this plant. The aim of this study was to investigate antioxidant activity of hydroalcoholic extract of the root of A. euchroma and its protective effect on hepatotoxicity induced by CCl4 in mice. In this experimental study, A. euchroma was extracted with ethanol solvent by macer...
[ 10 ] - Starting Dose Calculation for Medicinal Plants in Animal Studies; Recommendation of a Simple and Reliable Method
Background and purpose: Research studies indicate that almost 80% of the present day drugs are derived directly or indirectly from medicinal plants. The estimation of a safe starting dose is a concern when a new substance is to be investigated including medicinal plants, in clinical and laboratory studies. This study was intended to explore a simple and reliable method of calcu...
[ 11 ] - بررسی اثرات ضد سرطانی سنه سیونین و پیرگیاه در رده های سلولی سرطانی پروستات
Background and purpose: This research aimed at evaluating the effects of senecionine and Senecio vulgaris extract on apoptosis and cell cycle inhibition. Also, their cytotoxicity on prostate cancer cell lines (PC3, DU145 and HGFs), antioxidant effects, and influences on AR and CLU gene expression were investigated. Materials and methods: In this experimental study, senecionine and S. vulgaris ...
[ 12 ] - Anticancer Effects of Deoxypodophyllotoxin and Juniperus communis L. on Prostate Cancer Cell Lines
Background and purpose: In this study, the effects of a mixture of deoxypodophyllotoxin/DPT and Juniperus communis L. on apoptosis and cellular inhibition were evaluated. Also, their cytotoxicity effects on prostate cancer cells (PC3 and DU145) and normal cells (HGFs), their anti-inflammatory effects, oxidation properties, and their effects on the expression of androgen receptors (AR) and clust...
[ 13 ] - Antidiabetic Activity of Aqueous Seed Extract of Securigera securidaca in Streptozotocin Induced Diabetic Rats
Background & Objective: Securigera securidaca is a medicinal plant used in Persian folk medicine to decrease blood sugar. Nevertheless, there is some controversy about its effects. The current study investigated the hypoglycemic activity of the aqueous seed extract of S. securidaca. Materials & Methods: Sixty mature male Charles-River rats were categorized and divided randomly into 10 groups w...
[ 14 ] - Ethnobotanical Study of Medicinal Plants used in Skin Diseases in the Area Alamut-Qazvin, Iran
Background: Medicinal plants have been used for treatment of diseases and finding of new drugs. Botanical valuable traditional methods, offer finding new medicinal plants and herbal medicines. Objective: The aim of this study was the identification of important medicinal plants that widely were used by local inhabitants, in the treatment of skin diseases in the area of Alamut-Qazvin, Iran. M...
[ 15 ] - Effect of Prunus Mahaleb L. Seed Extract on Ethylene glycol- and Ammonium Chloride-Induced Urolithiasis in BALB/c Mice
Background: Kidney stone disease can be quite painful, recurrent, and affects many people. Despite advances in drug therapy, there is still a need to find effective drugs with fewer complications for long-term treatment of kidney stones and to prevent its recurrence. The present study aimed to evaluate the effect of Prunus mahaleb L. seed extract on ethylene glycol- and ammonium chloride-induce...
[ 16 ] - Protective Effect of Sankol Herbal Product on Kidney Stone in Balb/C Mice
Background and purpose: Kidney stone is a common form of kidney disease and many efforts have been made to find medications for its prevention and treatment. Current study evaluated the protective effects of Sankol herbal product in the formation of renal stone in male Balb/c mice. Materials and methods: Nephrolithiasis was induced in male Balb/C mice within 21 days by adding 75% ethylene glyc...
[ 17 ] - Qualitative and Quantitative Study of Pyrrolizidine Alkaloids in Medicinal Plants Sold in Herb Shops
Background and purpose: Pyrrolizidine alkaloids (PAs) are a group of chemical compounds that are seen as secondary metabolites in different plant families. These compounds can cause liver, kidney, and lung damages and their presence in various herbal products increases the risk of injury. This study aimed at performing qualitative and quantitative evaluation of pyrrolizidine alkaloids in medic...
[ 18 ] - Effect of a Herbal Medicine Containing Satureja hortensis L., Hypericum perforatum L. and Foeniculum vulgare L. on Patients with COVID-19 Infection
Background and purpose: This research aimed at investigating the effect of herbal medicine on reduction of pulmonary complications in patients with Coronavirus disease 2019 (COVID-19). Materials and methods: Forty patients with COVID-19 infection older than 18 years of age (60% men) with the average age of over 55 years old enrolled in this study. Written consent was obtained and participants...
[ 19 ] - Effect of Lipogel Containing Extracts of Eryngium campestre L. and Satureja hortensis L. on Wound Healing in Male Wistar Rats
Background and purpose: Wound is a type of injury with high prevalence in the society. The main requirement for wound management is rapid and complete wound healing without the spread of infection. Medicinal plants are affordable and accessible and suggested as one of the key treatment options. The aim of this study was to investigate the effect of lipogel formulations containing the extract...
[ 20 ] - Purification and Identification of Chemical Constituents of Basidiomycete Daedaleopsis tricolor Collected from Mazandaran Province, Iran
Background and purpose: Mushrooms are natural sources that have antitumoral effects, immunomodulatory and anti-oxidant effects. One of the fungus which remained intact is Daedaleopsis tricolor that belongs to the family of Polyporaceae. There are limited phytochemical investigations on other species of this genus, so, we aimed at performing a phytochemical analysis of this fungus. Materials a...
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