Objective: In a previous work, we showed that asafoetida essential oil (AEO), from oleo-gum resin of Ferula asafoetida L. from the Apiaceae family, has a vasodilatory effect. This effect was both endothelium-dependent and endothelium-independent. The present study was designed to determine whether potassium channels and intracellular calcium release contribute to AEO-i...

Ferula assa-foetida L. is distributed throughout central Asia and Mediterranean area and grows wildly in Iran and Afghanistan. Asafoetida is an oleo-gum-resin that is the exudates of the roots of Ferula assa-foetida and some other Ferula species. In Iranian traditional medicine, asafoetida is considered to be sedative, analgesic, carminative, antispasmodic, diuretic, antihelmintic, emmenagogue ...

Objective: Previous studies reported that asafetida from Ferula assa-foetida Linn. species and its essential oil (AEO) have antioxidant effects. In the present study, the effect of AEO was evaluated on ischemic-reperfusion injury in isolated rat hearts. Materials and Methods: Forty-eight male Wistar rats were divided into 6 groups: 1) control group, 2) vehicle group, 3-5) AEO groups and, 6) car...

Asafoetida, an oleo-gum-resin obtained from the roots of Ferula assafoetida, is used in traditional medicine to treat various diseases including, asthma, epilepsy, gastrointestinal disorders and influenza. The aim of the current study was to evaluate the hypoglycemic activity of the asafoetida extract in streptozotocininduced diabetic rats. Male Wistar rats were randomly divided into 5 groups, ...

OBJECTIVE(S) Based on knowledge from traditional herbal medicine, Ferula assa-foetida (asafoetida) has several therapeutic applications but there is less knowledge about its effect on neurons. MATERIALS AND METHODS In order to evaluate neuronal differentiation, neuronal like cells were stained against neuronal specific markers β-Tubulin III and MAP2. After establishment of neuronal differenti...

BACKGROUND In Ayurveda and traditional medicines of different countries such as Iran, America and Brazil, asafoetida has been used as an aphrodisiac agent. OBJECTIVE The present study was aimed to evaluate the effectiveness of asafoetida on spermatic and testicular parameters in treated rats. MATERIALS AND METHODS A total of 30 male Wistar rats divided equally to five groups (one control an...

which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective(s): Based on knowledge from traditional herbal medicine, Ferula assa-foetida (asafoetida) has several therapeutic applications but there is less knowledge about its effect on neurons. Materials and Methods: In order to evaluate neuronal differentiation, neuronal ...

Herbs and spices have been traditionally used for prevention and cure of many diseases. Hence, the present study was aimed to investigate the effects of aqueous and alcoholic extract of four different spices (asafoetida, ginger, cinnamon and cardamom) extracts on human breast adenocarcinoma cell line (MCF) and HEP-G2 cancer cell lines through in-vitro growth inhibitory assay. Both aqueous and a...