background aspergillus fumigatus (af) is responsible for 90% of human infections. the lung is the predominate site of infection. it is able to colonize in respiratory tract of asymptomatic population and changed clinical features from noninvasive to invasive according to immuncomponent state of individuals. the aim of the present study was to determine the frequency of af immunoglobulin (igg) a...

background there are several conventional, immunological and molecular techniques to diagnose the fungi that cause aspergillosis in biological samples; these methods have some advantages and disadvantages. objectives the current study aimed to evaluate different methods used in identification and diagnosis of fungi causing aspergillosis. materials and methods male western albino rats were provi...

background and purpose: actinomycetes have been discovered as source of antifungal compounds that are currently in clinical use. invasive aspergillosis (ia) due to aspergillus fumigatus has been identified as individual drug-resistant aspergillus spp. to be an emerging pathogen opportunities a global scale. this paper described the antifungal activity of one terrestrial actinomycete against the...

the opportunistic mould aspergillus is a ubiquitous fungus. diseases caused by aspergillus species are most commonly caused by aspergillus fumigatus. the spectrum of disease caused by aspergillus is dependent on the health of the immune system. the ranges of illnesses individuals acquire are aspergilloma, allergic bronchopulmonary aspergillosis, invasive aspergillosis, sinusitis, otomycosis, oc...

Aspergillus fumigatus is a saprophyte fungus, widely spread in a variety of ecologicalniches and the most prevalent aspergilli responsible for human and animal invasiveaspergillosis. The first step to develop novel and efficient therapies is the identificationand understanding of the key tolerance and virulence factors of pathogens. The mainfocus of the present study is to perform the similarit...

Aspergillus fumigatus endocarditis is one of the rarest and severest complications in cardiological patients. We describe a patient with an intracardial pacemaker who was diagnosed as having Aspergillus fumigatus endocarditis. Postmortem examination showed a large, Aspergillus-infected thrombus encased in the right ventricle, pulmonary trunk and main pulmonary branches.

Polymerase chain reaction amplification of repetitive DNA motifs allows discrimination of Aspergillus species. In a preliminary survey, the DNA fingerprints appear to be identical when isolates of Aspergillus fumigatus are compared. When a primer deduced from a prokaryotic repeat motif is used, Aspergillus fumigatus isolates originating from different patients or different anatomical locations ...

Invasive pulmonary aspergillosis is typically caused by a single Aspergillus species, most frequently Aspergillus fumigatus. Here we report that a lung transplant recipient developed invasive aspergillosis due to a mixed infection caused by Aspergillus flavus and A. fumigatus. The implications for this unusual finding are discussed.

The in vitro susceptibility of 105 clinical and environmental strains of Aspergillus fumigatus and Aspergillus flavus to antifungal drugs, such as amphotericin B, azoles, and echinocandins was evaluated by the broth microdilution method proposed by the European Committee on Antimicrobial Susceptibility Testing (EUCAST). Following the EUCAST-proposed breakpoints, 20% and 25% of the clinical and ...

background: this study was performed to determine antifungal activity of silver nanoparticles (nano-ag) compared to voriconazole on clinical and standard strains of aspergillus fumigatus. materials and methods: inhibitory potency of nano-ag was determined using microtiter broth dilution method. susceptibility tests were performed against a. fumigatus isolated from bal (bronchoalveolar lavage) o...