Atherosclerosis is a complex inflammatory disorder of the medium and large-sized arteries. Recent experiments demonstrated that atherosclerosis is a Th1 dominant autoimmune condition, whereas Th2 cells are rarely detected within the atherosclerotic lesions. Several studies have indicated that Th2 type cytokines could be effective in the reduction and stabilization of atherosclerotic plaque. The...

Objective: Finding compounds that could be used for prevention of atherosclerosis (AS) is highly desired. The present study evaluated the protective effects of Urtica dioica (UD, commonly known as stinging nettle) leaf ethanolic extract against high-fat diet-induced AS in rats. Materials and Methods: In this study, 40 male adult Sprauge-Dawley rats were randomly allocated to 4 equal groups and ...

Objective: The purpose of this study was to investigate the effect of coriander seed powder (CSP) on the atherosclerotic and cardioprotective indices in type 2 diabetic patients. Materials and Methods: In this study, fifty type 2 diabetic patients consumed 2 capsules of the CSP /day for a period of 6weeks. Blood samples were collected from the patients before and after the course of CSP consu...

Background and Objectives: Cardiovascular diseases are the most important cause of death in the world. Atherosclerosis, as a common form of cardiovascular disease, tends to involve specific areas of the circulatory system. Boron has anti-inflammatory and antioxidant properties with potential beneficial effects. In this study, we investigated the effect of Boron on histopathological changes of a...

Objective(s):Atherosclerosis is chronic inflammatory process triggered by oxidative stress. Oxidative stress can increase hydrogen peroxide (H2O2)level, which induce atherosclerosis through the processes such as formation of perivascular adipose tissue (PVAT), foam cells, and atherosclerotic plaque. Antioxidant is needed to control negative effects of oxidative stress. One source of antioxidant...

background : the aim of this study was to detect fungi in atherosclerotic plaques and investigate their possible role in atherosclerosis. methods : coronary atherosclerotic plaques specimen were obtained from patients with atherosclerosis. direct exami-nation, culture, histopathology study, pcr and sequencing were performed to detect/identify the mycotic elements in the plaques. age, sex, smoki...

conclusions a significant proportion of coronary atherosclerotic plaques in cadavers with confirmed acute myocardial infarction were detected to be infected with cytomegaloviruses while no infections of c. pneumoniae and h. pylori were detected. patients and methods sixty cadavers in two equal groups were analyzed. acute myocardial infarction group included cadavers with acute myocardial infarc...

Visceral artery aneurysms are rarely reported. They can occur in the context of a variety of underlying diseases. These aneurysms may coexist with non-visceral arterial aneurysms.Here we describe an 80-year-old man with concomitant superior mesenteric, celiac, renal, and aorto-bi-iliac aneurysms. The patient was a hypertensive and hyperlipidemic old man with history of transient ischemic attack...