نتایج جستجو برای: bovine cartilage
تعداد نتایج: 106221 فیلتر نتایج به سال:
Noninvasive methods of detecting cartilage degeneration can have an impact on identifying the early stages of osteoarthritis. Accurate measurement of sodium concentrations within the cartilage matrix provides a means for analyzing tissue integrity. Here a method is described for quantitating sodium concentration and visibility in cartilage, with general applications to all tissue types. The sod...
Paradoxically, bovine cartilage stimulates the immune system in resisting cancer and viruses, but suppresses it in rheumatoid diseases. Thus it acts as a “normaliser”. According to Dr. Pridden, “bovine cartilage closely resembles foetal mesenchyme, the primordial tissue from which muscle, bone, tendons, ligaments, skin, fat and bone marrow (the heart of the immune system) all develop.” “The car...
Cartilage matrix glycoprotein (CMGP) is a disulfide-bonded 550,000-dalton protein that is synthesized by chondrocytes and ciliary epithelial cells. We have purified the protein from bovine and porcine articular cartilage and have sequenced two peptides, which both have significant homology with human ceruloplasmin, a copper-binding oxidase. Immunolocation analysis indicates that a commercial po...
OBJECTIVE S The scarcity of articular cartilage defect to repair due to absence of blood vessels and tissue engineering is one of the promising approaches for cartilage regeneration. The objective of this study was to prepare an extracellular matrix derived decellularized bovine articular cartilage scaffold and investigate its interactions with seeded rat bone marrow mesenchymal stem cells (BM-...
Osteoarthritis (OA) is a common group of disabling joint disorders for which there are limited pharmacological therapies to alter disease progression. Zoledronate, one of several bisphosphonates found to modulate joint changes in animal OA models, may have a disease-modifying role, and potential mechanisms of action include effects on cartilage and/or subchondral bone. In OA cartilage, loss of ...
T he health care profession and patients continue to await solid evidence about the effects of shark or bovine cartilage in the treatment of angiogenesis-dependent disease states, Some evidence has accrued that shark cartilage may have efficacy in several common diseases, including but not limited to cancer. Zealots have made unsubstantiated claims about the benefits of therapy with shark and o...
N-terminal analysis of aggrecan fragments lost from bovine nasal cartilage cultured in the presence of recombinant human interleukin 1alpha revealed a predominant ARGSVIL sequence with an additional ADLEX sequence. Production of the ARGSVIL-containing fragments has been attributed to the action of a putative proteinase, aggrecanase. The minor sequence (ADLEX) corresponds to a new reported cleav...
OBJECTIVE Dickkopf-3 (Dkk3) is a non-canonical member of the Dkk family of Wnt antagonists and its upregulation has been reported in microarray analysis of cartilage from mouse models of osteoarthritis (OA). In this study we assessed Dkk3 expression in human OA cartilage to ascertain its potential role in chondrocyte signaling and cartilage maintenance. METHODS Dkk3 expression was analysed in...
protein-chondroitin sulfate bonds.8 No similar mammalian enzymes in joint tissues were found until Ziff, et al.' demonstrated an agent extracted from the synovial membrane in cases of acute rheumatoid arthritis and related this to its content of granulocytes. Since this type of inflammation is not usually seen in osteoarthritis, it is of considerable interest that Lack' has suggested blood plas...
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