Observation of the clinical outcomes in Temozolomide and radiotherapy Combination against metastatic brain tumors

the brain is a rare site for metastasis in most extracranial pediatric solid tumors, including wilm’s tumor. outcome for these patients are generally dismal. very few cases have been reported to have good survival even after therapy. this paper reports a case of stage iv wilm’s tumor with lung metastases in a patient who developed a solitary brain metastasis five months after completion of chem...

Background: Brain necrosis (RN) is a common radiotherapy sequela for brain metastases. Bevacizumab identified as therapeutic strategy RN. This study aimed to the clinical and radiobiological impacts on efficacy of in treating RN following stereotactic radiosurgery (SRS)

background: in order to assign appropriate planning target volume (ptv) margins, each centre should measure the patient positioning deviations for their set-up techniques. at the royal marsden hospital, uk, a conformal shell (cast) system is used when a stereotactic frame is not suitable. in this paper, we report on a series of measurements with the aim of obtaining the systematic and random co...

Introduction: Ionizing radiation is non-surgical treatment of brain tumors and metastases. Preclinical studies have showed main insights into harmful effects of radiation on the nervous system in vivo and in vitro. Cognitive impairment such as progressive memory, executive and attention performance deficits indicates a significant risk for patients experiencing conventional rad...

objective primary central nervous system lymphoma (pcnsl) is an extremely rare condition in childhood. we report the first case of pcnsl in a child in iran. clinical presentation a nine-year-old boy was referred to mofid hospital with the history of headache of four months and seizure of 2 months duration. magnetic resonance imaging of the brain revealed a hyper-intense lesion in left fronto-pa...

Brain metastases management is still controversial even though many trials are trying to define the respective roles of neurosurgery, whole-brain radiotherapy, single-dose stereotactic radiotherapy and fractionated stereotactic radiotherapy. In this article, we review data from trials that examine the role of radiosurgery and fractionated stereotactic radiotherapy in the management of brain met...