The intracellular non-bicarbonate buffering capacity of vertebrate muscle is mainly supported by the imidazole groups of histidine residues in proteins, free L-histidine in some fish species, and histidine-containing dipeptides such as carnosine, anserine, and balenine (ophidine). The proton buffering capacity markedly differs between muscle types and animal species depending on the ability for...

Chemical Buffering Extracellular buffers, including plasma proteins, phosphates, and bicarbonate, are the earliest defense against acidosis. The most prominent extracellular buffer is bicarbonate, which is highly abundant and acts as a dynamic buffer by independently regulating Pco2 through changes in alveolar ventilation. This feature increases buffering capacity by more than 10-fold. Bufferin...

PURPOSE The purpose of this preliminary study was to examine the relationship of caries risk, salivary buffering capacity, salivary pH, salivary quality (flow, consistency) and levels of Streptococcus mutans in relation to cigarette smoking. METHODS This clinical trial consisted of 53 volunteer patients receiving care in a university based dental hygiene clinic. Participants completed a ques...