Corneal collagen cross-linking with riboflavin and UVA light is a new therapeutic method for increase the biomechanical stability of the cornea through induction of new additional links between collagen fibers. The aim of this paper is to show the mechanism of action of this therapeutically method in different corneal diseases, for which this method can be applied: corneal ectasia, bullous kera...

PURPOSE To determine the leading indication for penetrating keratoplasty. MATERIAL AND METHOD The authors retrospectively performed a chart review of the hospital records of all patients who underwent penetrating keratoplasty at Maharaj Nakorn Chiang Mai Hospital between January 1996 and December 1999. RESULTS A total of 45 corneal transplants were performed. The leading indications for pen...

Deep lamellar endothelial keratoplasty (DLEK) has become an alternative procedure for bullous keratopathy. Herein, the histopathological characteristics of corneal wound healing after DLEK were reported. A 71-year-old man suffering from left psuedophakia bullous keratopathy received small incision DLEK. Twenty months later, another penetrating keratoplasty (PK) was performed because of the graf...

The objective is to evaluate the effects of phototherapeutic keratectomy (PTK) in bullous keratopathy patients. Phototherapeutic keratectomy was performed in a pseudophakic patient with corneal decompensation after lens extraction, with the excimer laser Nidek EC 5000 after manual corneal epithelial debridement. There was no pain after fifteen days the laser application and during the eight mon...

Pseudophakic bullous keratopathy is characterized by corneal stromal edema with epithelial and subepithelial bullae due to cell loss and endothelial decompensation through trauma during cataract surgery. Patients present decreased vision, tearing, and pain caused by ruptured epithelial bullae. Cataract affects approximately 20 million people worldwide, and this complication can occur in 1 to 2%...

PURPOSE To report a case of bullous keratopathy secondary to iridoschisis treated by non-Descemet's stripping automated endothelial keratoplasty (nDSAEK). CASE REPORT A 79-year-old woman was referred to our hospital with loss of vision in the left eye. Slit lamp examination of her left eye showed a shallow anterior chamber with cataract and schisis in the inferior quadrant of iris stroma. Bul...

The purpose of this study is to analyze the clinical experience and the effect of human amniotic membrane transplantation on pterygium excision and bullous keratopathy. From January 1999 to January 2001 at University Hospital »Sestre milosrdnice« amniotic membrane transplantation was performed consecutively in 21 eyes: 11 eyes with bullous keratopathy and 10 with recurrent pterygia. In the grou...

PURPOSE To evaluate histological changes in the corneal stroma in pseudophakic bullous keratopathy. METHODS Twenty-eight patients (28 eyes) with pseudophakic bullous keratopathy underwent therapeutic penetrating keratoplasty at Shandong Eye Institute between January 2006 and November 2011. The patients were divided into two groups according to the duration of bullous keratopathy (<1.0 year gr...

It has been shown in animal models that matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) are responsible for remodelling and neovascularization of the diseased cornea. Under normal conditions, MMPs are expressed at relatively low levels, which may increase in case of different corneal diseases. In this paper we have investigated gene expression of matrix metalloproteinase 2, matrix...