PURPOSE To describe the morphologic features of Fuchs corneal dystrophy and compare them with those of bullous keratopathy. METHODS This was an observational case series. The study group consisted of 32 corneal buttons with a diagnosis of Fuchs dystrophy and the comparison group consisted of 22 corneal buttons with bullous keratopathy. Morphologic analysis was performed of corneal buttons fro...

PURPOSE Expression of cellular adhesion molecules is altered in bullous keratopathy. The hypothesis that epithelial alterations in bullous keratopathy compromise the surface of the cornea and its glycocalyx was tested. METHODS Studies were performed on eight cases each of pseudophakic bullous keratopathy and healthy corneas. The number of epithelial cell layers was determined with a stereolog...

PURPOSE The aim of this study was to investigate transcriptional activities of genes encoding transforming growth factor (TGF)-beta isoforms in bullous keratopathy corneas. METHODS The study group consisted of 45 patients with bullous keratopathy (22 females and 23 males). The control group included 45 corneal donors (21 females and 24 males). Quantification of TGF-beta1, TGF-beta2, and TGF-b...

OBJECTIVES To evaluate the outcomes of amniotic membrane transplantation for symptomatic relief in patients with bullous keratopathy. MATERIAL AND METHOD This retrospective study included 17 eyes (17 patients) with bullous keratopathy presenting with intractable pain or discomfort. The patients were enrolled from January 2000 to December 2004. Amniotic membrane transplantation was performed. ...

PURPOSE Little is known about the behavior of the endothelial cell (EC) layer following keratoplasty. In vitro experiments suggested that the peripheral endothelium might have a higher regenerative capacity than the central endothelium, and some authors hypothesized that endothelial progenitor cells are present in the limbal area. Thus, we analyzed the corneal endothelial regenerative capacity ...

purpose: to determine the indications for penetrating keratoplasty (pk) in iran over an 11-year period. methods: all eye bank records of patients who underwent pk from 1994 to 2004 at ophthalmologic centers throughout iran were reviewed. results: during this 11-year period, a total of 19,668 cases were operated. the most common indication for penetrating keratoplasty was keratoconus (34.5%), fo...

Background & Aims: This study was carried out to determine the leading indications for corneal transplantation in Kerman province. Methods: Medical records of 186 patients underwent corneal transplantation during 3 years (2004-2006) in Shafa Medical Center were evaluated retrospectively. The initial diagnosis and causes of corneal grafting were recorded. Infectious keratitis (Bacterial, Fungal,...

Bullous Keratopathy is the presence of corneal epithelial bullae, resulting from corneal endothelial disease. Bullous Keratopathy is caused by oedema of the cornea, resulting from failure of the corneal endothelium to maintain the normally dehydrated state of the cornea. Most frequently, it is due to Fuchs corneal endothelial dystrophy or corneal endothelial trauma. Fuchs dystrophy is a genetic...

purpose: to evaluate the efficacy of riboflavin administration and ultraviolet a (uva) cross-linking on advanced symptomatic bullous keratopathy (bk). methods: 10 patients with symptomatic pseudophakic bullous keratopathy (pbk) were included. slit-lamp examination, visual acuity, foreign body sensation (fbs) and corneal thickness as measured by pentacam, were performed before corneal cross-link...