ABSTRACT: Pigeons are known for their capacity to harbor and spread several zoonotic agents. Studies have suggested that pigeons also relevant disseminators of multidrug-resistant strains. In this study, surrounding a veterinary hospital were sampled tested the presence pathogenic Escherichia coli, Salmonella spp., Staphylococcus Clostridioides (Clostridium) difficile. E. coli isolates from 19 ...

Faecal samples from 37 patients with cystic fibrosis and 40 control patients at the Brompton Hospital and the London Chest Hospital were examined for the presence of Clostridium difficile. The organism was isolated from 2 (17%) of control patients who were receiving antibiotics and from one (3.6%) of control patients who had no antimicrobial treatment. Thirty two per cent of the patients with c...

The toxins produced by Clostridium difficile share several functional properties with other bacterial toxins, like the heat-labile enterotoxin of Escherichia coli and cholera toxin. However, functional and structural differences also exist. Like cholera toxin, their main target is the disruption of the microfilaments in the cell. However, since these effects are not reversible, as found with ch...

AND EXPLANATION OF THE TEST Toxigenic Clostridium difficile is the leading cause of nosocomial infectious diarrhea in developed countries. An estimated 300,000 cases of C. difficile associated disease (CDAD) are seen per year in U.S. hospitals alone. 2 Clostridium difficile is the etiologic agent in approximately 25% of all cases of antibiotic-associated diarrhea. Virtually any antibiotic can p...

introduction: toxigenic clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. the pathogenicity of c. difficile is related to toxins a&b.; children with cancer are at risk of developing c. difficile infection (cdi) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. recently, due to higher sensitivit...

background and objectives: incidence of hospital-acquired diarrhea has increased rapidly and burn patients are at high risk of getting it. infection with c. difficile is the most common cause of antibiotic associated diarrhea. the aim of this study was to determine the baseline characteristics and clinical presentation of hospital-acquired diarrhea and compare c. difficile and non- c. difficile...

Clostridium difficile enterotoxin (D-1) was detected in 13 symptomatic and nine asymptomatic neonates in the neonatal intensive care unit by latex agglutination test but was not found in 18 healthy neonates in two other newborn nurseries. Environmental contamination in the intensive care unit may have been the cause. An association between the presence of enterotoxin and clinical symptoms is di...

Introduction: Toxigenic Clostridium difficile is the major cause of antibiotic-associated diarrhea, colitis, and pseudomembranous colitis. The pathogenicity of C. difficile is related to toxins A&B. Children with cancer are at risk of developing C. difficile infection (CDI) due to increased exposure to antibiotics, immunosuppression, and longer hospital stays. Recently, due to higher sensitivity...

Clostridioides difficile infection is expected to become the most common healthcare-associated worldwide. C. difficile-induced pathogenicity significantly attributed its enterotoxin, TcdA, which primarily targets Rho-GTPases involved in regulating cytoskeletal and tight junction (TJ) dynamics, thus leading cytoskeleton breakdown ultimately increased intestinal permeability. This study investiga...

OBJECTIVE To estimate prevalence and determine association between antimicrobia resistance and toxin gene profile of Clostridium difficile in commercial pigs at the preharvest food-safety level. ANIMALS 68 sows and 251 young pigs from 5 farms in North Carolina and 3 in Ohio. PROCEDURES Fecal samples were collected from sows (8/farm) and matched young pigs (32/farm) at farrowing and again at...