Despite its distance from the active site the flexible amino-terminal segment (NTS) in the β-domain of the plant sesquiterpene cyclase δ-cadinene synthase (DCS) is essential for active site closure and desolvation events during catalysis.

Six new cadinene sesquiterpenoids, xenitorins A-F (1-6), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia puerto-galerae. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

the volatile constituents of the aerial parts of varthemia. persica dc. var. persica, growing wild in iran, were investigated by gc-ms. sixty seven constituents were identified. ?-cadinene (9.7%), selin-11-en-4-?-ol (5.30%), germacrene d (4.9%), bicyclogermacrene (4.7%), ??muurolene (4.7%), ?-eudesmol (4.52%), ?-himachalen oxide (3.6%), ?-eudesmol (3.54%), ?-bourbonene (3.21%) were found to be ...

The hydrodistilled essential oils of the leaves and twigs of Litsea mushaensis and L. linii were analyzed. Sixty-nine and ninety compounds were identified in the leaf and twig oils, respectively, of L. mushaensis. The main components of the leaf oil were beta-eudesmol (24.2%), tau-cadinol (10.2%), alpha-humulene (10.1%), alpha-pinene (9.7%), and trans-beta-ocimene (6.5%), whereas the main compo...

Clionaterpene (1), a new cadinene sesquiterpene, along with six known compounds 2–7 were isolated from the marine sponge Cliona sp. The structure of 1 absolute configuration was determined by spectroscopic data (UV, IR, MS, and NMR) quantum chemical calculation. Compound first sesquiterpene metabolite this genus. In addition, cytotoxic antibacterial activities these evaluated. However, none the...