background: the aim of preliminary study was determined development process status of t-cell population lymphocytes in ukrainian children after 22 years from chernobyl accident for next feasibility study. material and method: 150 participants aged 6 to 16 years are included in three groups: group i (n=65), 30 to 60 km from center accident at zone 3th, group ii (n=65) 60 to 90 km from same locat...

Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Only a limited percentage of infected individuals develop disease in response to the virus while the majority remain asymptomatic and HAM/TSP is the most common clinical manifestation of the virus. HAM/TSP is an inflamma...

systemic lupus erythematosus (sle) is a chronic autoimmune disease which results in damage to various organs. some animal studies have revealed that activation of toll-like receptors (tlrs) is important in the pathogenesis of sle. in the present study, the percentage of different immune cell subsets in 35 sle patients and 38 control subjects was analyzed by flow cytometry. we also assessed the ...

the immune responses that develop following epstien-barr virus (ebv) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. to evaluate the immune response, flow cytometric analysis of the peripheral blood of six patients during the acute phase of ebv infection was performed. this analysis revealed a significant increase in the percentages and th...

The study included 24 patients, which formed the baseline group — 12 patients with pulmonary tuberculosis in combination COVID-19 infection and control tuberculosis. There were studied leukocyte formula, content of CD3, CD4, CD8 lymphocytes, NO2-+NO3- total its metabolites. obtained results showed that there is a pronounced decrease lymphocytes an unexpressed shift formula to left. lymphocyte d...

Background: Lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. Because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. Objective: To establish ...

background: type 2 diabetes (t2d) is a chronic metabolic disorder in which beta-cells are destroyed. the islet amyloid polypeptide (iapp) produced by beta-cells has been reported to influence beta-cell destruction. objective: to evaluate if iapp can act as an autoantigen and therefore, to see if cd8 + t-cells specific for this protein might be present in t2d patients. methods: peripheral blood ...