stem cells are of great interest for regenerating disturbed tissues and organs. these cells are commonly isolated from the bone marrow, but there has been interest in other tissues in the recent years. in this study, we evaluated the possibility of isolation of stem cells from oral connective tissue and investigated their characteristics.in this experimental study, sampling from the bone marrow...

objective(s) some investigation has indicated that adipose-derived stem cells possess different surface epitopes and differentiation potential according to the localization of fat pad from which the cells were derived. in the present study proliferation capacity and aging of such cells were explored. materials and methods adherent cells were isolated from the collagenase digests of adipose tiss...

introduction: her2/neu, a member of the epidermal growth factor receptor family, has been shown to be over-expressed in some tumors. the purpose of this study was to determine the salivary levels and tissue expression of her2/neu in patients with head and neck squamous cell carcinoma (hnscc) and their correlation with clinicopathologic parameters.   materials and methods: enzyme-linked immunoso...

in vitro culture systems using bone marrow cells from balb/c mice were set up in medium supplemented with spleen-derived medium. bone marrow cells grown in spleen-derived medium gave rise to cultures containing >97% mast cells. the cells were used in polarisation chemotaxis assays with the intention of determining the effect of nerve tissue-derived neurotransmitters on mast cell migration. some...

objective: cryopreservation of immature testicular tissue should be considered as an important factor for fertility preservation in young boys with cancer. the objective of this study is to investigate whether immature testicular tissue of mice can be successfully cryopreserved using a simple vitrification procedure to maintain testicular cell viability, proliferation, and differentiation capac...

human adipose tissue represents an abundant, practical and appealing source of donor tissue for autologous cell replacement. recent findings have shown that stem cells within the stromalvascular fraction of adipose tissue display a multilineage developmental potential. adipose tissue-derived stem cells can be differentiated towards adipogenic, osteogenic, chondrogenic,myogenic and neurogenic li...

background: the cultured mesenchymal stem cells (msc) have been used in many clinical trials however, there are still some concerns about the cultural conditions. one concern is related to the use of fbs as a widely used xenogeneic supplement in the culture system. human platelet-rich plasma (hprp) is a candidate replacement for fbs. in this study, the effect of hprp on msc proliferation and os...

Tissue and cell transplantation are regarded as a popular procedure in clinical sciences, prospecting a new horizon for several incurable diseases. Along with its usefulness, many ethical concerns accompany this development. The ethical issue of organ transplant is unique to the source used which includes: living related, living unrelated, cadaveric, and xenotransplant. Obtaining organs has a s...

Human adipose tissue represents an abundant, practical and appealing source of donor tissue for autologous cell replacement. Recent findings have shown that stem cells within the stromalvascular fraction of adipose tissue display a multilineage developmental potential. Adipose tissue-derived stem cells can be differentiated towards adipogenic, osteogenic, chondrogenic,myogenic and neurogenic li...