The potent neurotoxin kainate activates ion channel-forming receptors. However, it can also activate a G protein-coupled signaling pathway to inhibit transmitter release in central neurons. It remains unclear whether the same receptor complex is involved in both signaling activities. Here we show that in a population of dorsal root ganglion cells, exposure to kainate elicits a G protein-depende...

Due to geographic and climatic conditions in mountainous northwest area, Roads in these areas are often covered with snow, ice and mud. Hence Transportation of equipment and soldiers encounter hardship and difficulties in rural area and specially outposts. To solve these problems, it is needed to fabricate portable roadway or traction mats. These high strength mats cover surface of roads and ar...

the accumulative roll bonding (arb) as a severe plastic deformation (spd) procedure aimed at enhancing the mechanical properties of metals and alloys. in the present study, a new slab method is proposed for estimating the forming stress field for cold extrusion of metals cross the alumina interlayer powder particles by accumulative roll bonding process. plastic deformation behavior of the metal...

Polycystic kidney disease (PKD) family proteins associate with transient receptor potential (TRP) channel family proteins to form functionally important complexes. PKD proteins differ from known ion channel-forming proteins and are generally thought to act as membrane receptors. Here we find that PKD1L3, a PKD protein, functions as a channel-forming subunit in an acid-sensing heteromeric comple...

We have identified in organic solvent extracts of whole cells of the gram-positive pathogen Rhodococcus equi two channel-forming proteins with different and complementary properties. The isolated proteins were able to increase the specific conductance of artificial lipid bilayer membranes made from phosphatidylcholine-phosphatidylserine mixtures by the formation of channels able to be permeated...

In this paper, we consider a joint beam forming, power and channel allocation in a multi-user and multichannel underlay multiple input single output (MISO) cognitive radio network (CRN). In this system, primary users (PU’s) spectrum can be reused by the secondary user transmitters(SUTXs) to maximize the spectrum utilization while the intra-user interference is minimized by implementing bean for...