Angioedema can be caused by either mast cell degranulation or activation of the kallikrein-kinin cascade. In the former case, angioedema can be caused by allergic reactions caused by immunoglobulin E (IgE)-mediated hypersensitivity to foods or drugs that can also result in acute urticaria or a more generalized anaphylactic reaction. Nonsteroidal anti-inflammatory drugs (cyclooxygenase 1 inhibit...

OBJECTIVE To evaluate the impact of chronic urticaria on quality of life of outpatients through the university questionnaire Dermatology Life Quality Index (DLQI). METHODS Survey of the impact on quality of life caused by chronic urticaria, using the DLQI questionnaire validated for the Portuguese language. Patients were interviewed during visits to a specialized outpatient clinic between May...

omalizumab is a recombinant humanized anti-ig e monoclonal antibody used as the third line treatment of chronic spontaneous urticaria (csu). we report four patients with severe antihistamine-resistant csu, who developed angioedema, anaphylaxis and/or flare up of urticaria at different times following omalizumab therapy.

Chronic Urticaria (CU) is a skin disorder characterized by wheal and flare with duration of more than 6 weeks affecting 1%-2% the population (more common in women). Thirty to 35% cases CU have angioedema [1]. The etiology chronic spontaneous urticarial not usually clear, 40%-50% are idiopathic 30%-40% autoimmune [2, 3]. Quality life disturbed which has direct relation severity [4].

Chronic urticaria is a prolonged disease with unknown etiology and management.in order to determine the association of helicobacter pylori(H.pylori) infection with chronic urticaria,a case-control study was carried out in this regard 95 chronic urticaria patients without any underlying etiology and 190 healthy individuals who were matched for age and sex were evaluated by-anti-H.pylori IgG dete...

Amiodarone-induced angioedema: Amiodarone-induced angioedema: Amiodarone-induced angioedema: Amiodarone-induced angioedema: Amiodarone-induced angioedema: Report of two cases Report of two cases Report of two cases Report of two cases Report of two cases Sir, Amiodarone, a class II long-acting anti-arrhythmic, capable of blocking both α and β-adrenoceptors is an iodine-containing highly lipophi...

BACKGROUND Chronic urticaria affects patients by interfering with their daily activities, damaging their self-esteem and negatively affecting their interpersonal relationships. Healthcare professionals may underestimate the impact of the condition on patients' quality of life. OBJECTIVES To evaluate quality of life using one generic and one disease-specific health-related quality of life inst...

Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown pathogenesis. Nonsteroidal antiinflammatory and biologic drugs are used in its treatment. A 38 year old male patient diagnosed with AS was admitted to the rheumatology outpatient clinic due swelling both upper eyelids around eyes recurring for 1 month. He at 5th month etanercept With current clinic, etanercept-induced angi...

Omalizumab is a monoclonal antibody against IgE, nowadays approved for the treatment of persistent severe (EU) or moderate-to severe (USA) IgE-mediated asthma but there is also some evidence (case reports and four published clinical trials) on the effectiveness of this medication in urticaria and angioedema. The case of a 42-year-old woman suffering from severe allergic asthma and severe chroni...