نتایج جستجو برای: chronic hbv infection
تعداد نتایج: 912127 فیلتر نتایج به سال:
Background: Blood transfusion plays a great role in public health and the blood safety still has remained a main concern. HBV has been considered as one of the most prevalent blood borne infections. It is estimated that chronic HBV affects 350-400 million people worldwide. Comprehensive knowledge about HBV has high importance in Iran due to high number of blood dependent patients. Material ...
results findings showed that the genotype -607a/a is associated with the susceptibility to chronic hepatitis b. furthermore, allele c at position -137 is suggested to play a protective role against development of chronic hbv infection. conclusions host genetic factors play an important role in determining the outcome of hbv infection. it is suggested that il-18 genotype -607 a/a is associated w...
Background and purpose: Hepatitis B virus (HBV) is considered to be one of the most important etiological factors of liver complication around the world. Interactions of host immune responses with HBV have a crucial role in the outcome of the infection. IL12 is an important pro-inflammatory cytokine that stimulates natural killer cells and T-lymphocytes to produce IFN-γ, promotes T-helper...
800x600 hepatitis b virus (hbv) infection is the main cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma (hcc). several factors such as serum hbv dna level, genotype and specific viral mutations have been clarified to determine disease progression of chronic hepatitis b. among these, mutations can also occur in chronic hbv patients with antiviral treatment such as lamivudine the...
Chronic hepatitis B is still a major public health issue despite the successful prophylactic vaccination attempts. Chronicity of hepatitis B virus(HBV) is mainly due to its ability to debilitate host's immune system. Therefore, major measures have been taken to stop this process and help patients with chronic hepatitis B infection recover from their illness. While satisfactory results have been...
introduction: hepatitis b is a potentially life-threatening infection that causes acute infection and chronic hepatitis with progression to cirrhosis and hepatocellular carcinoma (hcc). interleukin-12 (il12) is responsible for activation of th1 immune responses, leading to possible clearance of hbv infection from the host’s body. the host’s immune-genetic background plays an important role in t...
Aims: Healthy gut microbiome plays a crucial role in the treatment of Hepatitis B Virus (HBV) infection and chronic liver disease. Based on existing studies, we aimed to explore difference efficacy Fecal Microbiota Transplantation (FMT) patients with different stages HBV-related Methods: In this study, 10 HBV HBeAg-negative infection, 8 Chronic (CHB) hepatitis cirrhosis Child-Pugh score A, 9 B/...
AIM To describe the characteristics of people diagnosed with acute and chronic hepatitis B virus (HBV) infection in British Columbia (BC). METHODS We used data from the BC Hepatitis Testers Cohort (BC-HTC), which includes all individuals tested for hepatitis C virus (HCV) or human immunodeficiency virus (HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990. These data were...
Background and purpose: Cytokines are a group of endogenous proteins which play an influential role in regulating the inflammatory responses and defeating infectious diseases. Elevated levels of proinflammatory cytokines and their receptors are usually observed in association with immune responses against viral infections such as hepatitis B virus (HBV) infection. IL 12 and its receptor play an...
conclusions the mir-155 appeared to be suppressed during hbv infection. the significantly higher mir-155 levels in alt-elevated patients infected with hbv suggest that mir-155 levels in pbmcs correlate with the immune state of patients with chronic hbv infection. results in the hbv-infected patients, the mir-155 levels were significantly lower than in the healthy controls (p = 0.001). chronic h...
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