BACKGROUND Lupoid cutaneous leishmaniasis (CL) is a rare form of CL having a striking resemblance to other granulomatous cutaneous conditions of infectious or inflammatory origin. The authors present a patient with a facial lupoid CL and discuss the diagnostic tools of this parasitological infection, the main differential diagnosis, and treatment. CASE REPORT A 54-year-old Tunisian woman, wit...

L eishmaniasis currently threatens 350 million people in 88 countries around the world. Ninety per cent of cutaneous leishmaniasis (CL) cases occur in Afghanistan, Brazil, Iran, Peru, Saudi Arabia, and Syria. An epidemic of cutaneous leishmaniasis is ongoing in Kabul, Afghanistan with an estimated 200 000 cases. Lesions can be very disfiguring, particularly on the face, which may have long term...

Background & Objective: There is a complicated interaction between leishmaniasis and the host immune cells, and also between the host immune cells. These interactions have fundamental effects on the outcome of the disease. The current study aimed at characterizing the number, distribution, co-localization, and interrelation of 4 types of inflamma...

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introduction: anthroponotic cutaneous leishmaniasis (acl) is still a major public health problem in the northeast and central parts of iran. this study was designed to compare microscopy and cultivation methods with pcr amplification of kinetoplast dna and its1 followed by rflp analysis for diagnosis of acute and chronic acl. methods: in this study, 66 patients with acl including 24 acute and 4...

BACKGROUND Interleukin (IL)-2 plays a central role in T cell-dependent immune responses. OBJECTIVES We conducted this study to determine and compare IL-2 expression in lupoid and usual types of Old World Cutaneous Leishmaniasis (OWCL), using immunohistochemistry. PATIENTS AND METHODS Thirteen paraffin-embedded specimens of lupoid and 12 specimens of usual types of OWCL were used. A mouse mo...

Lupoid leishmaniasis is an unusual complication of acute cutaneous leishmaniasis which can represent a diagnostic and therapeutic challenge. The disease is actually a reactivation of an earlier acute cutaneous infection. It usually starts close to or in the scar of previous lesion and can cause severe destruction. Its diagnosis is complicated by the sparsity of the microorganisms in the d...