AIM To investigate the relationship between non-alcoholic fatty liver disease (NAFLD) and colorectal adenomatous and hyperplastic polyps. METHODS A retrospective cross-sectional study was conducted on 3686 individuals undergoing health checkups (2430 males and 1256 females). All subjects underwent laboratory testing, abdominal ultrasonography, colonoscopy, and an interview to ascertain the ba...

Background and aims: Colonoscopic polypectomy and regular surveillance of colorectal polyps are important to prevent colorectal cancer. We aimed to evaluate the clinical characteristics of colorectal polyp and assess the predictive factors of colorectal polyp recurrence in 2 years after the first polypectomy. Methods: Total 194 patients with colorectal polyps underwent follow-up colonoscopy wit...

UNLABELLED Endoscopic polypectomy of colorectal polyps is a common procedure. However, endoscopic treatment of large polyps (those with a diameter exceeding 2 cm) remains questionable. There is a serious risk of colorectal carcinoma presence inside these lesions, which eventually would require surgical intervention. Apart from this fact endoscopic polypectomy of large polyps is connected with s...

To investigate the role of telomerase in the multistep Colorectal carcinogenesis, we examined telomerase activity in 31 adenomatous polyps and 22 paired cancer-normal mucosa specimens from non-hereditary nonpolyposis colorectal cancer patients. Telomerase activity was detected in 18% of normal mucosa, 16% of small «1.0 cm) polyps, 20% of intermediate polyps, 71% of large (>2.0 cm) polyps, and ...

Background: In western countries with high prevalence of colorectal cancers, colonic polyps are usually adenomatous. There are few studies from Iran regarding to the predominant type of polyps in colorectal area. Objectives: We conducted this retrospective study to evaluate the predominant colorectal polyps in our center as the largest referral center of the South region of Iran. Material and M...

BACKGROUND Hyperplastic polyps are common benign colorectal polyps, and are thought to have little association with malignant tumours in the colorectum. However, several reports suggest that some hyperplastic polyps may develop into colorectal neoplasms. AIM To clarify genetic alterations in colorectal hyperplastic polyps. METHODS Twenty eight colorectal polyps having serrated components we...

Colorectal polyps are classified as neoplastic or non-neoplastic on the basis of malignant potential. All neoplastic polyps should be completely removed because both the incidence of colorectal cancer and the mortality of colorectal cancer patients have been found to be strongly correlated with incomplete polypectomy. The majority of colorectal polyps discovered on diagnostic colonoscopy are di...

Background and aims: Colorectal adenomas are recognised as precursors of colorectal carcinomas. The significance of hyperplastic (metaplastic) colorectal polyps is unknown. The relationship between hyperplastic polyps and adenomas, and the prevalence and incidence of these lesions were evaluated in individuals predisposed to familial colorectal cancer. Methods: A total of 299 individuals partic...

PURPOSE Because colonoscopy after colorectal cancer surgery is important for detecting synchronous or metachronous colorectal neoplasms, we designed this study to investigate, by using postoperative colonoscopy, the miss rate for and the location of polyps remaining after colorectal cancer surgery. METHODS In a prospectively-collected patient database, 264 patients were shown to have undergon...