We investigated systematic differences in corpus callosum morphology in periventricular nodular heterotopia (PVNH). Differences in corpus callosum mid-sagittal area and subregional area changes were measured using an automated software-based method. Heterotopic gray matter deposits were automatically labeled and compared with corpus callosum changes. The spatial pattern of corpus callosum chang...

OBJECTIVES The purposes of this study were to construct reference limits for corpus callosum dimensions measured on images reconstructed from 3-dimensional (3D) sonography and to evaluate the reproducibility of these measurements. METHODS Three-dimensional sonographic volumes were acquired transabdominally from an axial view of the head in 361 fetuses cross-sectionally studied at 18 to 32 wee...

how to cite this article: singhal r, pandit s, saini a, singh p, dhawan n. the acrocallosal syndrome in a neonate with further widening of phenotypic expression. iran j child neurol. 2014 spring;8(2):60-64.   the presentation of the typical characteristics of the acrocallosal syndrome (acls) are hypoplasia/agenesis of corpus callosum, moderate to severe mental retardation, characteristic cranio...

OBJECTIVE Correlations between corpus callosum size and interhemispheric EEG coherence were investigated as measures of interhemispheric connectivity in patients with Alzheimer's disease. METHODS 11 patients underwent both magnetic resonance imaging and quantitative electroencephalography to assess corpus callosum size and interhemispheric coherence. For comparison, corpus callosum size was m...

The corpus callosum is the brain’s primary pathway for interhemispheric communication between the left and right hemispheres, and abnormal function and anatomy of the corpus callosum have been associated with a variety of disorders in humans and animals. In this study, we mapped quantitative trait loci (QTLs) modulating corpus callosum size in mice. By using mouse brain sections and stereologic...

Studies with MRI have shown differences in corpus callosum size between schizophrenic patients and controls. Most have found that the corpus callosum is smaller in schizophrenic patients, but in only a minority was this finding statistically significant, perhaps due to small sample sizes. Therefore a meta-analysis of 11 published studies of corpus callosum morphology in schizophrenia was conduc...

The glial cells of the cerebral cortex were examined and counted in 60-80g rats by light and electron microscopy and compared to those described in the corpus callosum by MORI and LEBLOND. The oligodendrocytes represented about 50% of all glial cells in the cortex and were less numerous than in the corpus callosum. They showed the three subtypes, light, medium dense and dense described in the c...

Neuronal survival in multiple sclerosis (MS) and other demyelinating diseases depends on the preservation of myelin and remyelination of axons. Myelin protection is the main purpose to decrease myelin damage in the central nervous system (CNS). Ursolic acid (UA) as a natural product in apple is suggested to protect neural cells. This study is the first to demonstrate an effect for UA on CNS mye...

Neuronal survival in multiple sclerosis (MS) and other demyelinating diseases depends on the preservation of myelin and remyelination of axons. Myelin protection is the main purpose to decrease myelin damage in the central nervous system (CNS). Ursolic acid (UA) as a natural product in apple is suggested to protect neural cells. This study is the first to demonstrate an effect for UA on CNS mye...

microphthalmia is defined as a globe with a total axial length that is at least two standard deviations below the mean for age. it may be isolated or part of a syndrome with other associated anomalies. causes can be divided into environmental, heritable or unknown. some researchers believe that microphthalmia and anophthalmia belong to one family. unilateral and bilateral anophtalmia have been ...