Etofenamate is a non-steroidal anti-inflammatory drug (NSAID). Clinical findings caused by etofenamate are uncommon. Allergic contact dermatitis is the most common cutaneous reaction reported. But petechial eruption due to etofenamate had not been reported yet. This report concerns an 11-year old male with petechial eruption after application of topical etofenamate. Physicians need to be aware ...

Adverse drug reactions are a major hazard of modern medicine. Fixed drug eruption, which is a cutaneous adverse drug reaction, is commonly seen with antimicrobials and analgesics. Here we report 37-year-old female with bullous fixed drug eruptions due to doxycycline administration.

Dermatomyositis (DM) is an idiopathic autoimmune connective disease characterized by muscles and skin inflammation of and a well-recognized association with several human malignancies, especially breast cancer. Paclitaxel is a taxane antineoplastic agent with therapeutic effects against a wide range of cancers including breast cancer. This drug is well known for neurotoxicity and hypersensitivi...

The drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a severe adverse drug-induced reaction which includes a severe skin eruption, fever, hematologic abnormalities (eosinophilia or atypical lymphocytes) and internal organ involvement. The most frequently reported drug was anticonvulsants. The diagnosis of DRESS syndrome is challenging because the pattern of cutaneous eru...

Sir, Sertraline (Zoloft1) is a new selective inhibitor of serotonin re-uptake. This family of antidepressant drugs is considered to be safe, and cutaneous adverse reactions have rarely been reported (1). We report here a patient who developed StevensJohnson syndrome (SJS) after starting treatment with sertraline (Zoloft1). A 96-year-old woman was admitted with a cutaneous and mucosal eruption. ...

Fixed drug eruption is a cutaneous reaction which occurs by repetitive exposure to the offending drugs like antimicrobials, anticonvulsants and NSAIDS. Here we are presenting a case of 65 year old male of fixed drug eruptions due to administration of injections diclofenac sodium. Diclofenac is a commonly used anti inflammatory drug for relieving pain.

Introduction Fixed drug eruption (FDE) is a pattern of a drug-induced skin reaction. It is characterized by skin erythematous plaques that recur at the same site each time the drug is administered. Several drugs have been associated to such cutaneous reaction, including, anticonvulsant agents, sulfonamides, non opioid analgesics and tetracyclines. Non steroidal anti-inflammatory drugs (NSAIDs) ...

Background: Serious cutaneous eruptions caused by cytarabine are never reported in China. Methods: We admitted a 43-year-old man who was diagnosed with acute non-lymphocytic leukemia, and was given several chemotherapy regimens including cytarabine. And when FLAG regimens were given in the patient, the serious pustular eruption appeared. Results: After the treatment, cutaneous eruption was grad...

Maculopapular or morbilliform eruptions may be the most common of all cutaneous drug reactions. It is also known that cutaneous drug reactions present the specific morphological patterns. (Figs. 10.1-1 and 10.1-2). In diagnosing skin diseases, it is essential to consider drugs as a possible cause of any eruption, because drug eruptions can take the form of any skin lesion. Drug eruptions may be...

Background: Drugs can cure, suppress or prevent a disease and are usually beneficial to humans. However, they can also produce undesirable / harmful effects, which are known as adverse drug reactions. These are important cause of morbidity, hospitalization, increased health expenditure and even death. Cutaneous adverse drug reactions are among the most frequent adverse drug reactions. Active se...