AIM Excessive dissolve of corneal tissue induced by MMPs which were activated by cytokins and chemokines will lead to corneal ulcer. The molecular mechanism of Lipoxin A4 (LXA4) on corneal collagen degradation in three dimensions was investigated. METHODS Rabbit corneal fibroblasts were harvested and suspended in serum-free MEM. Type I collagen, DMEM, collagen reconstitution buffer and cornea...

BACKGROUND Natural endometrium in Frozen-thawed Embryo Transfer (FET) may have some benefits upon implantation in patients with Repeated Implantation Failure (RIF). It might be due to possible differences between natural and stimulated endometrial growth factors and cytokins secretions. OBJECTIVE The objective of this study was to compare the pregnancy rate of FET on modified natural cycle ve...

Purpose. To detect the levels of transform growth factors- β (TGF- β1 , TGF- β2 β3) interferon- ʏ (INF- ), matrix metalloproteinase-9 (MMP-9) and S100B protein in blood serum patients with type 2 diabetes mellitus (DM) to reveal connection these factors neurodegenerative changes retina. Material methods. 30 patients, averagely aged 60.3, DM no signs diabetic retinopathy (DR) (the main group) he...

Age-related macular degeneration (ARMD) is a multiple etiology disease in which a broad range of genes and proteins play significant roles.1 Wet or exudative ARMD, also known as neovascular ARMD, is the type which causes most loss of vision. Neovascularization is an active and inflammatory condition (cytokins, growth factors and inflammatory cells) in which the initial stage could be the intera...

statement of the problem periodontal disease is a periodontal tissue inflammation caused by gram-negative and other bacteria. the release of various cytokins and mediators, including nitric oxide, in the inflammation area usually has determental effects on the periodontium, potentiating the inflammatory process. in order to prevent this side effect, investigatiors have used anti-oxidants such a...

background: natural endometrium in frozen-thawed embryo transfer (fet) may have some benefits upon implantation in patients with repeated implantation failure (rif). it might be due to possible differences between natural and stimulated endometrial growth factors and cytokins secretions. objective: the objective of this study was to compare the pregnancy rate of fet on modified natural cycle ve...