introduction: biocompatibility is a desirable feature for root-end filling materials. in this study we aimed to compare a new material called cold ceramic (cc) with intermediate restorative material (irm) and mineral trioxide aggregate (mta) using methyl-tetrazolium bromide (mtt) assay. materials and methods: the materials were tested in fresh and set states: (n=108). the cytotoxicity was compa...

background & objective: chlorhexidine solution is one of the widely used mouth antiseptic liquid that prevents teeth tissue damage and also has application as a root canal antiseptic. in this study, cytotoxicity of 2% chlorhexidine solution is compared with another root canal antiseptic, calcium hydroxide powder. materials and methods: cell cytotoxicity of both chemicals was assessed on culture...

The aim of this study was to evaluate and compare the cytotoxicity induced by two resin-based sealers, 2Seal and AH Plus, in two osteoblast-like cell lines, MG-63 and Saos-2. Using sterile discs of both sealers in complete media, 24- and 72-h extracts were prepared. The extracts were exchanged with Saos-2 or MG-63 cell culture media at 75% confluence, and after 24 h incubation, cell viability t...

The cytotoxicity of a series of 29 experimental alloys and six pure metals was determined with cell culture techniques and succinic dehydrogenase histochemistry. The width of any ring of inhibition, optical density of the histochemically stained cells, and a visual ranking of the intensity of the blue color of the stained cells were compared for determination of cytotoxicity. Twenty-four of the...

Cytotoxicity tests of zinc sulfide (ZnS) and cadmium sulfide (CdS) quantum dots (QDs) synthesized via all-aqueous process with various surface conditions were carried out with human endothelial cells (EA hy926) using two independent viability assays, i.e., by cell counting following Trypan blue staining and by measuring Alamar Blue (AB) fluorescence. The ZnS QDs with all four distinct types of ...

Alternatives to animal testing are being used assess the safety of raw ingredients during process developing cosmetics. However, since cosmetic products composed a variety ingredients, product itself should also be tested. In this study, we attempted evaluate skin irritation potential lotions by modifying existing alternative test methods. To commercial in form an objective indicator, calculate...

Fetal tissue from primiparous hamsters prevented simian virus 40 (SV40) tumorigenesis in male hamsters, whereas fetal tissue from multiparous hamsters did not. The parity status of normal (uninoculated) hamsters also influenced the cytotoxicity of their lymphoid cells against tumor cells. Lymph node cells from nonpregnant primiparous and multiparous animals were cytotoxic in microcytotoxicity t...

This study was planned to explore the capability of nanoemulsions (NEs) consisting of CapryolTM 90 and oleic acid for the delivery of rapamycin (RAP). Permeability and cytotoxicity of RAP-loaded NEs were also inspected. Pseudo-ternary phase diagrams were created with oleic acid and CapryolTM 90 (as oil phase) and four surfactants and co-surfactants at various weight ratios (Rsm). Selected NEs f...