To explore the potential molecular mechanism of Oxoglaucine(OG) in treatment Breast Cancer(BC) based on network pharmacology and bioinformatics. TCMSP SwissTargetPrediction databases search for OG Related targets, GeneCards database finds all BC-related targets. Take intersection BC as targets that inhibit BC. All are topologically analyzed by Cytoscape 3.7.1 software, finally core target is ob...

UNLABELLED Our current biological knowledge is spread over many independent bioinformatics databases where many different types of gene and protein identifiers are used. The heterogeneous and redundant nature of these identifiers limits data analysis across different bioinformatics resources. It is an even more serious bottleneck of data analysis for larger datasets, such as gene lists derived ...

DAVID (Database for Annotation, Visualization and Integrated Discovery) is a bioinformatics resource developed by the National Institute of Allergy and Infectious Diseases at Frederick in conjunction with the Laboratory of Immunopathogenesis and Bioinformatics (LIB), SAIC Frederick. This resource is described as “a graph theory evidence-based method to agglomerate speciesspecific gene/protein i...

LINE-1 and the cell cycle: protein localization and functional dynamics Paolo Mita, Aleksandra Wudzinska, Xiaoji Sun, Joshua Andrade, Shruti Nayak, David J. Kahler, Sana Badri, John LaCava, Beatrix Ueberheide, Chi Y. Yun, David Fenyo, Jef D. Boeke Institute of Systems Genetics (ISG), Department of Biochemistry and Molecular Pharmacology, NYU Langone Medical Center, New York NY 10016. Proteomics...

M. Carey Satterfield, Gwonhwa Song, Kelli J. Kochan, Penny K. Riggs, Rebecca M. Simmons, Christine G. Elsik, David L. Adelson, Fuller W. Bazer, Huaijun Zhou, and Thomas E. Spencer Department of Animal Science, Texas A&M University, College Station, Texas; Department of Biology, Georgetown University, Washington, District of Columbia; Centre for Bioinformatics and Computational Genetics, Univers...

SIMON R. HARRIS,'' DAVIDE PISANI,' DAVID J. GOWER, AND MARK WILKINSON 7 Department of Zoology, The Natural History Museum, London, SW7 5BD, UK; E-mail: [email protected] (S.R.H.) School of Earth Sciences, University of Bristol, Bristol BS8 IK], UK School of Biology and Psychology, Division of Biology, University of Newcastle-upon-Tyne, NEl 7RU, UK Bioinformatics Laboratory, The National Un...

The Potential Role of Androgenesis in Cytoplasmic–Nuclear Phylogenetic Discordance SHANNON M. HEDTKE1,2,∗ AND DAVID M. HILLIS1,2 1Section of Integrative Biology and 2Center for Computational Biology and Bioinformatics, University of Texas at Austin, Austin, TX 78712, USA; E-mail: [email protected]; ∗Correspondence to be sent to: Section of Integrative Biology, University of Texas at Austi...

“The authors thank the patients for consenting to research. In addition, they acknowledge Alona Sosinsky and the Imperial College BRC Genomics facility for bioinformatics support. They acknowledge Generation Scotland for providing control samples and thank Shona Kerr and Archie Campbell for assistance in provision of Generation Scotland samples. The authors acknowledge Cat Graham for providing ...

NMR Structure Improvement: A Structural Bioinformatics & Visualization Approach. by Jeremy N. Block Department of Biochemistry Duke University Date:_______________________ Approved: ___________________________ David C. Richardson, Co-Supervisor ___________________________ Jane S. Richardson, Co-Supervisor ___________________________ John D. York ___________________________ Pei Zhou ____________...

David J. Balding .Imperial College School of Medicine, London/ I extendmy apologies to the authors that an unavoidable commitment arising unexpectedly in the 18 hours before the meeting robbed me of my final preparation, so that my comments at the meeting were poorly presented. I shall try to do a better job in this written version, and to leave enough space I shall omit my introductory comment...