Back ground: Candida albicans is a member of the normal human microflora. C. albicans cell wall is composed of several protein and carbohydrate components which have been shown to play a crucial role in C. albicans interaction with the host immune system. Major components of C. albican cell wall are carbohydrates such as mannans, β glucans and chitins, and proteins that partially modulate the h...

Background: Dendritic cells (DC) induce tumor or pathogen-specific T cell responses in humans. Several laboratories have developed culture systems, including maturation factors for human DC from peripheral blood monocytes. We comprehensively compared standard maturation stimulus, an autologous monocyte-conditioned medium (MCM), with heparin for their ability to promote uniformly mature DC that ...

dendritic cells (dcs) induce pathogen-specific t cell responses. we comprehensively studied the effects of addition of maturation stimulus, fibroblasts (fibroblast conditioned medium), pha activated t cells (t cell conditioned medium), and mixture of fibroblast & pha activated t cells (fcm-tccm) conditioned media on maturation of dcs. monocytes were cultured with gm-csf and il-4 for five da...

objective: the aim of the present study was to investigate the effect of protein and dna components of toxoplasma gondii on maturation of dendritic cells and their efficiency in il-12 production and proliferation of t cells. materials and methods: for dc generation, bone marrow cells were cultured in the presence of gm-csf and il-4 for 5 days. tumor lysate and protein or dna components of toxo...

back ground: candida albicans is a member of the normal human microflora. c. albicans cell wall is composed of several protein and carbohydrate components which have been shown to play a crucial role in c. albicans interaction with the host immune system. major components of c. albican cell wall are carbohydrates such as mannans, β glucans and chitins, and proteins that partially modulate the h...