نتایج جستجو برای: denervation
تعداد نتایج: 6945 فیلتر نتایج به سال:
BACKGROUND Renal denervation is a new treatment considered for several possible indications. As new systems are introduced, the incidence of acute renal artery wall injury with relation to the denervation method is unknown. We investigated the acute repercussion of renal denervation on the renal arteries of patients treated with balloon-based and nonballoon-based denervation systems by quantita...
There is a bidirectional, causal relationship between obstructive sleep apnea (OSA) and hypertension. OSA-related hypertension characterized by high rates of masked hypertension, elevated nighttime blood pressure, nondipper pattern nocturnal abnormal pressure variability. Hypoxia/hypercapnia-related sympathetic activation key pathophysiological mechanism linking the 2 conditions. Intermittent h...
Letter by Wang Regarding Article, “Renal Denervation for the Treatment of Cardiovascular High Risk-Hypertension or Beyond?” To the Editor: In their article titled “Renal denervation for the treatment of cardiovascular high risk-hypertension or beyond?” Böhm et al presented an excellent overview on renal denervation and its clinical indications. The authors emphasized the blood pressure– lowerin...
Abstract Peripheral nervous system (PNS) is an important component of the tumor microenvironment (TME). It has been established that autonomic innervation plays role in cancer. However, effect afferent (sensory) neurons on progression remains unclear. Utilizing surgical and chemical skin sensory denervation methods, we showed supported growth melanoma tumors vivo demonstrated limited activation...
Skeletal muscle denervation causes muscle atrophy via complex molecular mechanisms that are not well understood. To better understand these mechanisms, we investigated how muscle denervation increases growth arrest and DNA damage-inducible 45α (Gadd45a) mRNA in skeletal muscle. Previous studies established that muscle denervation strongly induces Gadd45a mRNA, which increases Gadd45a, a small m...
We studied the effects of slow continuous hemorrhage (0.5 ml/kg per min) on measurements of arterial and left atrial pressures, and renal nerve activity in conscious dogs with all reflexes intact, or after sinoaortic baroreceptor denervation, cardiac denervation, or sinoaortic baroreceptor denervation plus vagal denervation. In intact dogs, mean arterial pressure remained relatively constant at...
The DENERHTN trial (Renal Denervation for Hypertension) confirmed the blood pressure (BP) lowering efficacy of renal denervation added to a standardized stepped-care antihypertensive treatment for resistant hypertension at 6 months. We report here the effect of denervation on 24-hour BP and its variability and look for parameters that predicted the BP response. Patients with resistant hypertens...
An 8-year-old female Japanese Spitz dog was reffered to Shiraz University Veterinary Clinic, with signof anisocoria. Clinical examinations revealed mydriasis in the right eye. Ocular examination revealed adilated and unresponsive right pupil to focal illumination. By testing with topical 2% pilocarpine, thetentative diagnosis was parasympathetic denervation of the right iris sphincter muscle—pu...
We studied the effects of slow continuous hemorrhage (0.5 ml/kg per min) on measurements of arterial and left atrial pressures, and renal nerve activity in conscious dogs with all reflexes intact, or after sinoaortic baroreceptor denervation, cardiac denervation, or sinoaortic baroreceptor denervation plus vagal denervation. In intact dogs, mean arterial pressure remained relatively constant at...
Renal artery denervation has recently emerged as a novel therapy for patients with resistant hypertension. Clinical results from renal sympathetic denervation support the safety and efficacy of this method over a period of 18 months. However, several limitations have been reported. Previous studies have shown that chemical denervation by vincristine is safe and effective in an experimental mode...
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