نتایج جستجو برای: diabetic nephropathies

تعداد نتایج: 111533  

Journal: :international journal of preventive medicine 0
farzaneh rohani nakysa hooman sedighe moradi mehdi mobarra mehri najafi zadeh

background: hypertension is more common in adults with type 1 diabetes mellitus (t1dm) than the general population. the aim of this study was to detect the pre-hypertensive stage in children with t1d and to evaluate its correlation with diabetic nephropathy compared to non-diabetic children. methods: this was a prospective cross-sectional study in an out-patient clinic of a university hospital....

Journal: :nephro-urology monthly 0
yanchun qu tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected]; tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected] yue zhang tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected] yue zhang tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected] shengzhi li tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected] ruifa han tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected] mengsheng qiu tianjin institute of urology, 2nd hospital of tianjin medical university, 300211, china +86-2288326390, [email protected]

background bone morphogenetic protein 7 (bmp7) has been suggested to play a protective role against kidney injury in chronic kidney disease. objectives to identify the critical molecular regulators in the early stage of diabetic nephropathy, we studied the expression of bmp7 and 2 important kidney-specific markers, podocin and tamm–horsfall protein (thp). materials and methods a diabetic nephro...

Journal: :Best Practice & Research Clinical Endocrinology & Metabolism 2021

Diabetic kidney disease (DKD) represents a growing public health burden and is the leading cause of end-stage diseases. In recent years, host-gut microbiota interactions have emerged as an integral part for host homeostasis. context nephropathies, mounting evidence supports bidirectional microbiota-kidney crosstalk, which becomes particularly manifest during progressive dysfunction. Indeed, in ...

2017
Irena Kostovska Katerina Tosheska Trajkovska Svetlana Cekovska Goce Spasovski Danica Labudovic

In the last two decades a great progress was observed in understanding of podocytes, their specific structure and function identifying many specific podocyte proteins, such as nephrin and podocalyxin. Podocytes form the final barrier to plasma proteins leakage. Nephrin as a main component of the filtration diaphragm forms a physical barrier while podocalyxin as sialoglycoprotein forms an electr...

Journal: :Lancet 2005
Piero Ruggenenti Annalisa Perna Giacomina Loriga Maria Ganeva Bogdan Ene-Iordache Marta Turturro Maria Lesti Elena Perticucci Ivan Nediyalkov Chakarski Daniela Leonardis Giovanni Garini Adalberto Sessa Carlo Basile Mirella Alpa Renzo Scanziani Gianbattista Sorba Carmine Zoccali Giuseppe Remuzzi

BACKGROUND In chronic nephropathies, inhibition of angiotensin-converting enzyme (ACE) is renoprotective, but can further renoprotection be achieved by reduction of blood pressure to lower than usual targets? We aimed to assess the effect of intensified versus conventional blood-pressure control on progression to end-stage renal disease. METHODS We undertook a multicentre, randomised controll...

2013
Ye Jin Kim Yoo Hyung Kim Ki Dae Kim Kang Ryun Moon Jae Ho Park Bo Mi Park Hyewon Ryu Dae Eun Choi Ki Ryang Na Kwang Sun Suh Kang Wook Lee Young Tai Shin

BACKGROUND The aim of this study was to evaluate the clinical characteristics of nondiabetic nephropathy in type 2 diabetes mellitus patients and to find a clinical significance of renal biopsy and immunosuppressive treatment in such a patient. METHODS Renal biopsy results, clinical parameters, and renal outcomes were analyzed in 75 diabetic patients who underwent kidney biopsy at Chungnam Na...

Journal: :Journal of the American Society of Nephrology : JASN 2006
Gema Fernandez-Juárez Vicente Barrio Soledad García de Vinuesa Marian Goicoechea Manuel Praga José Luño

There is clear evidence that pharmacologic blockade of the renin-angiotensin system (RAS) with angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) reduces proteinuria and slows the progression of renal disease in diabetic and nondiabetic nephropathies, a beneficial effect that is not related to BP control. Some patients exhibit a significant beneficial respons...

Journal: : 2022

Abstract. The aim of this study was to evaluate the contribution kidney biopsy performed with an appropriate indication diagnosis and treatment in diabetic patients nephropathy.
 Methods: In retrospective 32 type 2 diabetes who underwent a single center between 2012-2019 were included. Kidney indications determined as without retinopathy proteinuria above 1 g/day.
 Results: Diabetic (...

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