Rutin and naringenin, two phenolic compounds with antioxidant properties were encapsulated in lipid-based onion-type multilamellar vesicles (MLVs). After vesicles formation, the free, adsorbed/encapsulated analytes were well separated with size exclusion chromatography (SEC), and rutin and naringenin were quantified with UV-HPLC at 258 nm and 290 nm. A mathematical model was developed to separa...

The purpose of this study was to develop a gene vector electrostatically assembled with a polysaccharide capsule. We used pDNA/polyethylenimine (PEI) complexes as efficient non-viral vectors. The pDNA/PEI complex was electrostatically encapsulated with various polysaccharides such as fucoidan, lambda-carrageenan, xanthan gum, alginic acid, hyaluronic acid, and chondroitin sulfate (CS). The pDNA...

in induction of systemic and mucosal immunity, particulate antigens are more effective than soluble antigens possibly because they are more efficiently endocytosed by mucosal-associated lymphoid tissue (malt) m cells. in this study, we determined the systemic and mucosal immune responses in rabbits following intranasal immunization of tetanus toxoid tt and cpg-odn encapsulated within plga nanos...

the use of essential oils as the preservative agents in food industry faces the problem of interactions with food matrix components, low solubility in aqueous phase, high volatile character and sensitivity to environmental conditions. the aim of this study was to enhance thermal stability and antioxidant activity of thyme essential oil (to) by encapsulation in chitosan nanoparticles (cs-np). to...

Hydrogels can promote desirable cellular phenotype by mimicking tissue-like stiffness or serving as a gene delivery depot. However, nonviral gene delivery inside three-dimensional (3D) hydrogels remains a great challenge, and increasing hydrogel stiffness generally results in further decrease in gene delivery efficiency. Here we report a method to enhance nonviral gene delivery efficiency insid...

Lemon essential oils (LEOs) as a bioactive compound with antioxidative potential are used as safe additives in foods. However, this compound is sensitive to light, oxidation, and processing in order to solve this problem encapsulation could be a suitable technique to protect them from degradation. The aim of this study was to produce nano-encapsulated LEOs in Chitosan: Modified Starch (Hicap) t...

An oral infectious disease, dental caries, is caused by the cariogenic streptococci Streptococcus mutans. The expected preventive efficiency for prophylactics against dental caries is not yet completely observed. Nisin, a bacteriocin, has been demonstrated to be microbicidal against S. mutans, and liposome-encapsulated nisin improves preventive features that may be exploited for human oral heal...

The ability of encapsulated Burkholderia cepacia G4 (ATCC 53617) for trichloroethylene (TCE) degradation (1.5, 5, 10, and 20mg/L) in the presence of toluene (10 and 60mg/L) as enhancement substrate was evaluated experimentally. Burkholderia cepacia G4 cultures were encapsulated in cylindrical pellets (4mm in diameter and 4mm in height (preferred)) using polyethylene glycol (PEG). Higher transfo...