Erythema multiforme is a cutaneous reaction pattern precipitated by varied agents, notably herpes simplex and drugs. It predominantly occurs in adolescents and young adults but may be seen at other ages also. While vaccination is rarely a precipitating factor for erythema multiforme, it may occasionally be seen in infants and children. We report here a case of a two month-old infant with lesion...

BACKGROUND It was proposed that Stevens-Johnson syndrome and toxic epidermal necrolysis differed from erythema multiforme majus by the pattern and localization of skin lesions. OBJECTIVE To evaluate the validity of this clinical separation. DESIGN Case-control study. SETTINGS Active survey from 1989 to 1995 of 1800 hospital departments in Europe. PATIENTS A total of 552 patients and 172...

Erythema multiforme is a skin condition considered to be a hypersensitivity reaction to infections or drugs. It consists of a polymorphous eruption of macules, papules, and characteristic "target" lesions that are symmetrically distributed with a propensity for the distal extremities. There is minimal mucosal involvement. Management involves treating the existing infectious agent or discontinui...

Sorafenib is a new therapeutic agent being used in metastatic renal cell carcinoma, hepatocellular carcinoma, and malignant melanoma. The most frequently seen cutaneous side effects due to sorafenib are erythema, exfoliative dermatitis, acne vulgaris, and flushing. Folliculitis, eczema, and erythema multiforme are other, rare side effects of sorafenib. A 59-year-old man underwent left radical n...

ERYTHEMA exudativum multiforme is a specific skin disease of unknown aetiology which may be associated with various syndromes in which the mucous membranes-conjunctiva, lips, bronchi and ano-genital region-are affected, and consequently fall in the domain of the dermatologist, physician, ophthalmologist and uro-genital surgeon. As its name implies, erythema multiforme is characterised by the va...