orf is a mucocutaneous disease that occurs when non-intact skin comes into contact with contaminated sheep saliva. the lesions may complicate to lymphangitis or secondary bacterial infection, but systemic complications such as erythema multiforme, maculopapular rash, and generalized lymphadenopathy are rare. in this paper, we present two cases of erythema multiforme following orf disease.

Rowell syndrome (RS) describes the rare presentation of EM like lesions found in association with a diagnosis lupus erythematosus (LE). Major diagnostic criteria includes LE, EM, and anti-nuclear antibodies. Minor chilblains, anti-Ro/anti-La antibodies, rheumatoid factor. We present 26-year-old white male seen consultation for chronic erythema multiforme (EM) duration 6 months unresponsive to t...

Erythema multiforme is acute mucocutaneous condition that considered to be immune- mediated hypersensitivity reaction medicine or an infection. There are described three forms of erythema multiforme: “minor form”, “major form” and oral multiforme. It presents  a diagnostic dilemma due varied possible manifestations. Diagnosis often made based on history clinical examination. In this articl...

Oral erythema multiforme presents with oral and lip ulcerations typical of erythema multiforme but without skin target lesion. The primary attack is confined to oral mucosa but subsequent attacks can produce more severe forms of erythema multiforme involving skin. It is important to distinguish it from other oral ulcerative disorders for early diagnosis and treatment. Here we report a case of o...

Erythema multiforme is an acute mucocutaneous disorder, characterized by varying degrees of blistering and ulceration. We report a case of recurrent herpes-associated erythema multiforme managed with prophylactic acyclovir. An 11-year-old boy had lesions in the oral cavity and lips, which had been diagnosed as erythema multiforme minor. Four months later, the patient had desquamative gingivitis...

Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness.