Although it is well-admitted that transcranial Direct Current Stimulation (tDCS) allows for interacting with brain endogenous rhythms, the exact mechanisms by which externally-applied fields modulate the activity of neurons remain elusive. In this study a novel computational model (a neural mass model including subpopulations of pyramidal cells and inhibitory interneurons mediating synaptic cur...

Alport syndrome and encapsulating peritoneal sclerosis (EPS) are both rare diseases. Their joint occurrence is highly unlikely. Two patients at our center with Alport syndrome developed EPS. We therefore hypothesized that Alport syndrome might predispose to the development of EPS and that this predisposition might be reflected in a fast peritoneal transport rate at baseline. We compared the mas...

drug induced dystonic reactions are among common presentations of patients in emergency departments, and typically occur with antidopaminergic agents as their extra-pyramidal side effects. dystonic reactions usually occur within the first few hours or days after commencing a drug or dose increase. unlike other extra-pyramidal side effects, a patient may experience acute dystonic reactions (adrs...

Down syndrome, the leading genetic cause of intellectual disability, results from an extra-copy of chromosome 21. Mice engineered to model this aneuploidy exhibit Down syndrome-like memory deficits in spatial and contextual tasks. While abnormal neuronal function has been identified in these models, most studies have relied on in vitro measures. Here, using in vivo recording in the Dp(16)1Yey m...

Objective: Neuroleptic malignant syndrome (NMS) is a rare, but life-threatening condition associated with the use of antipsychotics. Although NMS is mainly associated with typical antipsychotics, it can also be induced by atypical antipsychotics. In this paper, we report a case of NMS associated with clozapine use and describe the classic and atypical manifestations of NMS. The case and discuss...

Introduction: Hypoglycemia is an emergency. If untreated, it can result persistent neuronal injury of the central nervous system. The neurologic manifestations of hypoglycemia ranges from headache, seizure, different neuropsychiatric symptoms to stupurous, coma and stroke like symptoms. Akinetic­rigid syndrome, a severe form of extra pyramidal symptom is rarely described with hypoglycemic brain...

QCD corrections to the gluino induced contribution to b → sγ are shown to be important in order to extract reliable bounds on the off-diagonal elements of the squark mass matrices. Talk presented by Tobias Hurth at the International Euroconference on High Energy Physics (EPS-HEP99), 15-21 July 1999, Tampere, Finland. Indirect Search for Supersymmetry

Aim: The present study investigated the preventive effect and probable mechanism of ethanolic extract of Limonia acidissima (EELA) stem bark as compared to standard (L-dopa) in phenothiazine induced extra pyramidal side effects (catatonia) in experimental rats. The acute as well as chronic dose of chlorpromazine (CPZ) was administered to induce catatonia. Settings and Design: In case of acute s...